KCTD13

Description		potassium channel tetramerization domain containing 13
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GO Annotations	Cellular Component	Nucleoplasm Nuclear Body Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Protein Domain Specific Binding Small GTPase Binding Identical Protein Binding
	Biological Process	Cell Migration Protein Ubiquitination Negative Regulation Of Rho Protein Signal Transduction Stress Fiber Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of DNA Replication Positive Regulation Of Synaptic Transmission Protein Homooligomerization Neural Precursor Cell Proliferation
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Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Hand grip strength ( 29691431) Menarche (age at onset) ( 25231870) Schizophrenia ( 28991256 25056061 29483656 30285260) Urinary sodium excretion ( 31409800)
Interacting Genes		21 interacting genes: ADRB2 ARMC7 CDC37 CRK CUL3 EXOSC5 GORASP2 KAT7 KCTD10 LNX1 NTAQ1 NUDT18 PCNA POLD2 POLR1C PPARG PSMA1 RHOA TNFAIP1 VTA1 ZMYND19
Entrez ID		253980
HPRD ID		12339
Ensembl ID		ENSG00000174943
Uniprot IDs		A0A3B3IS45 Q8WZ19
PDB IDs		4UIJ
Enriched GO Terms of Interacting Partners?
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