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UBR2

Description ubiquitin protein ligase E3 component n-recognin 2
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GO Annotations Cellular Component
  • Ubiquitin Ligase Complex
  • Chromatin
  • Nucleus
  • Cytoplasm
  • Cytosol
Molecular Function
  • Protein Binding
  • Zinc Ion Binding
  • Ubiquitin Protein Ligase Activity
  • Leucine Binding
Biological Process
  • Protein Polyubiquitination
  • Chromatin Silencing
  • Reciprocal Meiotic Recombination
  • Male Meiotic Nuclear Division
  • Male Meiosis I
  • Spermatogenesis
  • Negative Regulation Of Transposition
  • Protein Ubiquitination
  • Negative Regulation Of TOR Signaling
  • Histone H2A Ubiquitination
  • Cellular Response To Leucine
  • Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway
Pathways
  • Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
  • Lung cancer in never smokers ( 28604730)
  • Obesity-related traits ( 23251661)
  • Serum total protein level ( 29403010)
Interacting Genes 9 interacting genes: H2AC20 H2BC8 NTAN1 NTAQ1 PKN1 SUOX UBE2B UBE2D2 UBE2H
Entrez ID 23304
HPRD ID 09853
Ensembl ID ENSG00000024048
Uniprot IDs B3KXG6 Q8IWV8
PDB IDs 3NY2 3NY3 5TDA 5TDB 5TDD 5UM3
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025