TYMP

Description		thymidine phosphorylase
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GO Annotations	Cellular Component	Cytosol
	Molecular Function	1,4-alpha-oligoglucan Phosphorylase Activity Protein Binding Growth Factor Activity Thymidine Phosphorylase Activity Pyrimidine-nucleoside Phosphorylase Activity Protein Homodimerization Activity
	Biological Process	Mitochondrial Genome Maintenance Angiogenesis Pyrimidine Nucleobase Metabolic Process Pyrimidine Nucleoside Metabolic Process Chemotaxis Signal Transduction Cell Differentiation Regulation Of Myelination Pyrimidine Nucleoside Salvage DTMP Catabolic Process Pyrimidine Nucleoside Catabolic Process Regulation Of Transmission Of Nerve Impulse Regulation Of Gastric Motility
Pathways		Pyrimidine salvage Pyrimidine catabolism
Drugs		Tipiracil
Diseases		Mitochondrial DNA depletion syndrome (MDS)
GWAS		Blood metabolite levels ( 24816252) Blood protein levels ( 30072576) Chronic lymphocytic leukemia ( 28165464) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 29403010 32888494 20139978 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494) Red blood cell count ( 32888494 27863252) Red blood cell traits ( 23222517) Red cell distribution width ( 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		4 interacting genes: ERBB2 LINC01554 MESD ZMYND12
Entrez ID		1890
HPRD ID		08833
Ensembl ID		ENSG00000025708
Uniprot IDs		B2RBL3 E5KRG5 P19971
PDB IDs		1UOU 2J0F 2WK5 2WK6
Enriched GO Terms of Interacting Partners?
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