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DAPK1
Description
death associated protein kinase 1
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Actin Cytoskeleton
Molecular Function
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Calmodulin-dependent Protein Kinase Activity
Protein Binding
Calmodulin Binding
ATP Binding
GTP Binding
Syntaxin-1 Binding
Identical Protein Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
Protein Phosphorylation
Apoptotic Process
Regulation Of Autophagy
Positive Regulation Of Autophagy
Negative Regulation Of Translation
Intracellular Signal Transduction
Regulation Of Apoptotic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Protein Autophosphorylation
Cellular Response To Interferon-gamma
Cellular Response To Hydroperoxide
Apoptotic Signaling Pathway
Regulation Of NMDA Receptor Activity
Pathways
Caspase activation via Dependence Receptors in the absence of ligand
Drugs
5,6-Dihydro-Benzo[H]Cinnolin-3-Ylamine
Phosphoaminophosphonic Acid-Adenylate Ester
6-(3-AMINOPROPYL)-4,9-DIMETHYLPYRROLO[3,4-C]CARBAZOLE-1,3(2H,6H)-DIONE
Fostamatinib
Diseases
Bladder cancer
GWAS
Blood pressure (
24954895
)
Cognitive function (
24684796
)
Gut microbiota (bacterial taxa, rank normal transformation method) (
32572223
)
Height (
31562340
)
Immune reponse to smallpox (secreted IFN-alpha) (
22610502
)
Night sleep phenotypes (
27126917
)
Ovarian cancer (
30557369
)
Post bronchodilator FEV1/FVC ratio (
26634245
)
Response to gemcitabine in pancreatic cancer (
22293537
)
Interacting Genes
107 interacting genes:
ABL1
ABLIM1
AHDC1
APEX2
ARRDC1
ARRDC1-AS1
ATF6
BAG2
BAIAP2
C11orf65
CALM1
CAPRIN1
CBLB
CCDC149
CDC42EP3
CDC42SE1
CMTM4
CNTROB
DENND1C
DTWD1
DUS1L
DUX3
EPHA1
FADD
FAM107A
FAM126B
FBXL14
FBXW11
FIBP
GASK1B
GTF2F1
IKBKG
JHY
LIMA1
LIMS1
LINC02875
LMF2
LNX1
LOXL2
MAPK1
MAPK3
MCM10
MDM2
MIB1
MRGBP
MTHFD2
MYL12B
NCBP3
NECAB1
NECAP1
NR3C1
ORMDL2
PAK6
PAPSS2
PCP4
PHKG2
PIM1
PIM2
POLR2M
PPP1R14A
PPP2R1A
PPP2R2D
PPP2R5A
PRKAG2
PRR16
PWP1
RAPGEF3
RASGRP2
RCHY1
RFC5
RHBDD1
RPAP3
RPL41
SARNP
SCEL
SCRN3
SCYL1
SGK2
SH2D2A
SLAIN2
SNRPA
SNURF
SNX9
SPATS2
SPRR2G
SRSF10
STARD3
STUB1
STX1A
TAS2R60
TBC1D22B
TNFRSF1A
TPD52L1
TRADD
TRAPPC2
TTC27
TUBB4B
UNC5A
UNC5B
UNC5C
VGLL4
VN1R1
WWTR1
YWHAB
ZAP70
ZMAT4
ZMYM5
Entrez ID
1612
HPRD ID
02902
Ensembl ID
ENSG00000196730
Uniprot IDs
B4DHI4
P53355
Q59H88
PDB IDs
1IG1
1JKK
1JKL
1JKS
1JKT
1P4F
1WVW
1WVX
1WVY
1YR5
2W4J
2W4K
2X0G
2XUU
2XZS
2Y0A
2Y4P
2Y4V
2YAK
3DFC
3DGK
3EH9
3EHA
3F5G
3F5U
3GU4
3GU5
3GU6
3GU7
3GU8
3GUB
3ZXT
4B4L
4PF4
4TL0
4TXC
4UV0
4YO4
4YPD
5AUT
5AUU
5AUV
5AUW
5AUX
5AUY
5AUZ
5AV0
5AV1
5AV2
5AV3
5AV4
6AAR
6FHA
6FHB
6GY5
6IN4
6QMO
6QN4
Enriched GO Terms of Interacting Partners
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