COL6A2

Description		collagen type VI alpha 2 chain
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Extracellular Space Endoplasmic Reticulum Lumen Protein-containing Complex Sarcolemma Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle
	Molecular Function	Protein Binding Collagen Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength
	Biological Process	Cell Adhesion Response To Glucose Extracellular Matrix Organization
Pathways		Collagen degradation Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions ECM proteoglycans ECM proteoglycans NCAM1 interactions Collagen chain trimerization
Drugs
Diseases		Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy
GWAS		Central corneal thickness ( 32528159 29760442) Height ( 31562340) Intraocular pressure ( 29235454) Refractive error ( 32231278)
Novel Interacting Genes		3 novel interacting genes: COL6A1 ERG RUNX1
Interacting Genes		5 interacting genes: ABCD3 COX6A2 FN1 SIRPA SLC38A3
Entrez ID		1292
HPRD ID		02110
Ensembl ID		ENSG00000142173
Uniprot IDs		A0A384MDP3 P12110
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?