MAN1B1

Description		mannosidase alpha class 1B member 1
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Integral Component Of Membrane Cytoplasmic Vesicle Endoplasmic Reticulum Quality Control Compartment Extracellular Vesicle
	Molecular Function	Mannosyl-oligosaccharide 1,2-alpha-mannosidase Activity Calcium Ion Binding
	Biological Process	Protein Glycosylation N-glycan Processing Oligosaccharide Metabolic Process Ubiquitin-dependent ERAD Pathway Protein Alpha-1,2-demannosylation Trimming Of Terminal Mannose On B Branch Trimming Of Terminal Mannose On C Branch Trimming Of First Mannose On A Branch Trimming Of Second Mannose On A Branch Endoplasmic Reticulum Mannose Trimming Mannose Trimming Involved In Glycoprotein ERAD Pathway
Pathways		Defective MAN1B1 causes MRT15 ER Quality Control Compartment (ERQC) Maturation of spike protein
Drugs		1,4-Butanediol Methyl-2-S-(Alpha-D-Mannopyranosyl)-2-Thio-Alpha-D-Mannopyranoside Kifunensine Duvoglustat
Diseases
GWAS		Initial alcohol sensitivity ( 30276832)
Novel Interacting Genes		1 novel interacting genes: WDR5
Interacting Genes		1 interacting genes: DNM2
Entrez ID		11253
HPRD ID		05068
Ensembl ID		ENSG00000177239
Uniprot IDs		Q9UKM7
PDB IDs		1FMI 1FO2 1FO3 1X9D 5KIJ 5KK7
Enriched GO Terms of Interacting Partners?
Tagcloud ?