AFG3L2

Description		AFG3 like matrix AAA peptidase subunit 2
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane M-AAA Complex
	Molecular Function	ATP-dependent Peptidase Activity Metalloendopeptidase Activity Protein Binding ATP Binding Metallopeptidase Activity Zinc Ion Binding Unfolded Protein Binding
	Biological Process	Proteolysis Mitochondrial Calcium Ion Transmembrane Transport Axonogenesis Neuromuscular Junction Development Mitochondrial Fusion Protein Processing Protein Autoprocessing Nerve Development Membrane Protein Proteolysis Mitochondrial Protein Processing Calcium Import Into The Mitochondrion Regulation Of Multicellular Organism Growth Cristae Formation Myelination Muscle Fiber Development Mitochondrial Calcium Ion Homeostasis Righting Reflex Protein-containing Complex Assembly
Pathways		Processing of SMDT1
Drugs		ATP
Diseases		Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS
Interacting Genes		5 interacting genes: APP MAPK8IP2 PHC2 RAC2 RNF167
Entrez ID		10939
HPRD ID		05205
Ensembl ID		ENSG00000141385
Uniprot IDs		Q8TA92 Q9Y4W6
PDB IDs		2LNA 6NYY
Enriched GO Terms of Interacting Partners?
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