HPSE

Description		heparanase
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Lysosome Lysosomal Membrane Extracellular Matrix Specific Granule Lumen Lysosomal Lumen Intracellular Membrane-bounded Organelle Membrane Raft
	Molecular Function	Beta-glucuronidase Activity Protein Binding Heparanase Activity Syndecan Binding
	Biological Process	Glycosaminoglycan Catabolic Process Proteoglycan Metabolic Process Cell-matrix Adhesion Positive Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Blood Coagulation Heparan Sulfate Proteoglycan Catabolic Process Positive Regulation Of Osteoblast Proliferation Neutrophil Degranulation Regulation Of Hair Follicle Development Positive Regulation Of Hair Follicle Development Positive Regulation Of Protein Kinase B Signaling Angiogenesis Involved In Wound Healing Vascular Wound Healing
Pathways		HS-GAG degradation Neutrophil degranulation
Drugs
Diseases
GWAS		Age-related cognitive decline (executive function) (slope of z-scores) ( 30954325)
Novel Interacting Genes		1 novel interacting genes: IRF4
Interacting Genes
Entrez ID		10855
HPRD ID		05286
Ensembl ID		ENSG00000173083
Uniprot IDs		Q9Y251
PDB IDs		5E8M 5E97 5E98 5E9B 5E9C 5L9Y 5L9Z 5LA4 5LA7 6ZDM
Enriched GO Terms of Interacting Partners?
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