PMVK

Description		phosphomevalonate kinase
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GO Annotations	Cellular Component	Peroxisome Cytosol Membrane Extracellular Exosome
	Molecular Function	Phosphomevalonate Kinase Activity Protein Binding ATP Binding
	Biological Process	Cholesterol Biosynthetic Process Sterol Biosynthetic Process Phosphorylation Isopentenyl Diphosphate Biosynthetic Process, Mevalonate Pathway Regulation Of Cholesterol Biosynthetic Process Response To Cholesterol
Pathways		Cholesterol biosynthesis Activation of gene expression by SREBF (SREBP)
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015 22544366) Bipolar disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) HDL cholesterol ( 24097068) HDL cholesterol levels ( 28334899) Inflammatory bowel disease ( 27569725) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Prostate cancer ( 23535732)
Interacting Genes		4 interacting genes: DDIT4L MCPH1 ZNF177 ZNF559-ZNF177
Entrez ID		10654
HPRD ID		07404
Ensembl ID		ENSG00000163344
Uniprot IDs		Q15126 Q6FGV9
PDB IDs		3CH4
Enriched GO Terms of Interacting Partners?
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