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CCT2
Description
chaperonin containing TCP1 subunit 2
Image
GO Annotations
Cellular Component
Zona Pellucida Receptor Complex
Extracellular Region
Cytosol
Chaperonin-containing T-complex
Microtubule
Azurophil Granule Lumen
Cell Body
Extracellular Exosome
Molecular Function
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Binding
Protein Folding Chaperone
Unfolded Protein Binding
Biological Process
Protein Folding
Binding Of Sperm To Zona Pellucida
Positive Regulation Of Telomere Maintenance Via Telomerase
Neutrophil Degranulation
Protein Stabilization
Chaperone Mediated Protein Folding Independent Of Cofactor
Chaperone-mediated Protein Complex Assembly
Positive Regulation Of Telomerase Activity
ScaRNA Localization To Cajal Body
Toxin Transport
Positive Regulation Of Establishment Of Protein Localization To Telomere
Positive Regulation Of Protein Localization To Cajal Body
Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways
Prefoldin mediated transfer of substrate to CCT/TriC
Formation of tubulin folding intermediates by CCT/TriC
Folding of actin by CCT/TriC
Association of TriC/CCT with target proteins during biosynthesis
Association of TriC/CCT with target proteins during biosynthesis
BBSome-mediated cargo-targeting to cilium
Neutrophil degranulation
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs
Diseases
GWAS
Height (
18391951
)
Logical memory (delayed recall) in normal cognition (
29274321
)
Urinary albumin excretion (
30220432
)
Urinary albumin excretion (no hypertensive medication) (
30220432
)
Urinary albumin-to-creatinine ratio (
31630189
31511532
)
Interacting Genes
23 interacting genes:
ACTA1
ACTB
CCT4
EEF2
ERLIN2
ESR1
FCHSD2
HSP90AB1
HSP90B1
LINC01554
NPSR1
PRPF40A
PSMC6
PSMD2
PTEN
RPS3
SUMO2
SUMO4
TUBA1B
VAV2
VRK2
YWHAG
ZNRD2
Entrez ID
10576
HPRD ID
06895
Ensembl ID
ENSG00000166226
Uniprot IDs
P78371
V9HW96
PDB IDs
6NR8
6NR9
6NRA
6NRB
6NRC
6NRD
6QB8
Enriched GO Terms of Interacting Partners
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