PROCR

Description		protein C receptor
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Centrosome Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Cell Surface Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding Signaling Receptor Activity
	Biological Process	Blood Coagulation Negative Regulation Of Coagulation
Pathways		Common Pathway of Fibrin Clot Formation Cell surface interactions at the vascular wall
Drugs		Drotrecogin alfa Phosphatidylethanolamine Tetradecyl hydrogen sulfate (ester)
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Anticoagulant levels ( 22216198) Blood protein levels ( 28240269) Coronary artery disease ( 29212778 33020668) D-dimer levels ( 21502573) Diastolic blood pressure ( 27618447) Factor VII activity ( 30642921) Factor VII activity or levels ( 30642921) Factor VII levels ( 20231535) Fish- and plant-related diet ( 32066663) HDL cholesterol levels ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Height ( 23563607) Hemostatic factors and hematological phenotypes ( 22443383) Protein C levels ( 28082259 25376901 20802025) Prothrombin time ( 22703881 29403010) Thrombosis ( 26908601) Ulcerative colitis ( 23128233) Venous thromboembolism ( 25772935 31420334) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		3 interacting genes: DMTN PROC VKORC1
Entrez ID		10544
HPRD ID		02801
Ensembl ID		ENSG00000101000
Uniprot IDs		Q9UNN8
PDB IDs		1L8J 1LQV 3JTC 4V3D 4V3E 6SNY
Enriched GO Terms of Interacting Partners?
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