MED12 and SGCE

		MED12	SGCE
Description		mediator complex subunit 12	sarcoglycan epsilon
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Membrane Mediator Complex	Golgi Apparatus Cytoskeleton Plasma Membrane Integral Component Of Plasma Membrane Dystrophin-associated Glycoprotein Complex Sarcoglycan Complex Dendrite Membrane Sarcolemma
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Beta-catenin Binding Protein C-terminus Binding Protein Domain Specific Binding Nuclear Receptor Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding Ubiquitin Protein Ligase Activity
	Biological Process	Neural Tube Closure Regulation Of Transcription By RNA Polymerase II Endoderm Development Heart Development Oligodendrocyte Development Schwann Cell Development Protein Ubiquitination Stem Cell Population Maintenance Spinal Cord Development Post-anal Tail Morphogenesis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Neurocranium Morphogenesis Canonical Wnt Signaling Pathway Wnt Signaling Pathway, Planar Cell Polarity Pathway Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Axis Elongation Involved In Somitogenesis Embryonic Brain Development	Cell-matrix Adhesion Muscle Organ Development
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Uterine fibroids ( 31649266)
Interacting Genes		18 interacting genes: CDK8 ESR1 ESR2 GLI3 LYST MED1 MED13 MED26 MED29 MED8 MED9 NANOG PPARGC1A SGCE SOX9 SREBF1 TAF1 VDR	13 interacting genes: AKAP9 ARIH2 CDK14 CDK6 CWC15 CYP3A7 MED12 MTERF1 PDYN PPP1CC SEMA3C SYT13 TAC1
Entrez ID		9968	8910
HPRD ID		02176	04999
Ensembl ID		ENSG00000184634	ENSG00000127990
Uniprot IDs		Q93074	A0A0S2Z4P5 A0A2R8Y5J3 A0A2R8YGQ3 A0A2R8YH84 B4DP78 C9JR67 E9PEH6 O43556
PDB IDs
Enriched GO Terms of Interacting Partners?
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