SEC16A and MIA3

Number of citations of the paper that reports this interaction (PubMedID 28442536)
25

Data Source:
BioGRID (pull down)

		SEC16A	MIA3
Description		SEC16 homolog A, endoplasmic reticulum export factor	MIA SH3 domain ER export factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol ER To Golgi Transport Vesicle Membrane Organelle Membrane Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site	Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Binding	Protein Binding Cargo Receptor Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Autophagy Endoplasmic Reticulum Organization Golgi Organization Substantia Nigra Development Protein Exit From Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Golgi To Plasma Membrane CFTR Protein Transport Protein Stabilization Protein Localization To Endoplasmic Reticulum Exit Site Protein Localization To Plasma Membrane	Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Leukocyte Migration Exocytosis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endocytosis Endoplasmic Reticulum Organization Negative Regulation Of Cell Adhesion Protein Secretion Protein Transport Negative Regulation Of Cell Migration Vesicle Cargo Loading Wound Healing Lipoprotein Transport Protein Localization To Endoplasmic Reticulum Exit Site COPII-coated Vesicle Cargo Loading Cellular Response To Oxidised Low-density Lipoprotein Particle Stimulus Negative Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Lymphocyte Migration
Pathways		COPII-mediated vesicle transport	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Cargo concentration in the ER Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Basal cell carcinoma ( 31174203) Crohn's disease ( 28067908) Cutaneous squamous cell carcinoma ( 27424798 32041948) Eosinophil counts ( 27863252) Height ( 28552196) Inflammatory bowel disease ( 28067908) Monocyte percentage of white cells ( 32888494) Serum alkaline phosphatase levels ( 33547301) Squamous cell carcinoma ( 31174203) Triglyceride levels ( 32154731) Ulcerative colitis ( 28067908 21297633)	Coronary artery disease ( 32469254 29212778 30104761 26343387 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary heart disease ( 17634449 21378990) Myocardial infarction ( 33532862 26343387) Myocardial infarction (early onset) ( 19198609)
Interacting Genes		2 interacting genes: MIA3 SEC23A	16 interacting genes: CACNA1A CEP55 CLIC3 COL7A1 FXR2 HOMER3 HSD17B14 ITGAX LENG8 MTNR1B NCK2 PRDM14 SEC16A SEC23A SEC24C TRIM27
Entrez ID		9919	375056
HPRD ID		11075	18918
Ensembl ID		ENSG00000148396	ENSG00000154305
Uniprot IDs		F1T0I1 O15027	Q5JRA6
PDB IDs			5KYN 5KYU 5KYW
Enriched GO Terms of Interacting Partners?
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