MAGI2 and RAPGEF2

  • Number of citations of the paper that reports this interaction (PubMedID 10548487)
  • 25
  • Data Source:
  • HPRD (in vitro, in vivo)

MAGI2

RAPGEF2

Description membrane associated guanylate kinase, WW and PDZ domain containing 2 Rap guanine nucleotide exchange factor 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute lymphoblastic leukemia (childhood) ( 23007406)
  • Adult body size ( 32376654)
  • Adverse response to drug ( 30420678)
  • Airway wall thickness ( 25517131)
  • Bitter beverage consumption ( 31046077)
  • Body mass index ( 28892062 25673413)
  • Body size at age 10 ( 32376654)
  • Bronchopulmonary dysplasia ( 23897914)
  • Chronotype ( 30696823)
  • Computer vision syndrome ( 33941792)
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
  • General risk tolerance (MTAG) ( 30643258)
  • Hippocampal atrophy ( 19668339)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • LDL cholesterol levels x short total sleep time interaction (1df test) ( 31719535)
  • LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Lead levels in blood ( 25820613)
  • Low density lipoprotein cholesterol levels ( 33339817)
  • Mammographic density (dense area) ( 25342443)
  • Memory dysfunction in frontotemporal lobe dementia ( 29724592)
  • Metabolite levels ( 23823483)
  • Nicotine dependence ( 33144568)
  • Night sleep phenotypes ( 27126917)
  • Obesity-related traits ( 23251661)
  • Pursuit maintenance gain ( 29064472)
  • Refractive error ( 32231278)
  • Response to anti-depressant treatment in major depressive disorder ( 22041458)
  • Response to lamotrigine and valproic acid in genetic generalized epilepsy ( 32308125)
  • Schizophrenia ( 28991256 30285260)
  • Serum folate levels ( 29953918)
  • Total cholesterol levels ( 33339817)
  • Visceral fat ( 30942860)
  • Dietary fat liking ( 32516399)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Molybdenum levels ( 26025379)
  • Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes 25 interacting genes: ACVR2A ADGRB1 ADRB1 ARRDC3 ATN1 CRHR1 CTNNB1 CTNND2 DLGAP1 DLGAP2 DLGAP3 DLL1 DSCAML1 GRID2 MORN4 PDZD11 PLEKHF2 PLXNB3 PRRG4 PTEN RAPGEF2 RPS6KA1 SMAD3 SNRPB TGFA 13 interacting genes: CTNNB1 HSPA1A IL16 KIF5A KIF5B MAGI2 MOB4 MT-ATP8 NEDD4 RALGDS RAP1A RAP2B SPP1
Entrez ID 9863 9693
HPRD ID 16212 19358
Ensembl ID ENSG00000187391 ENSG00000109756
Uniprot IDs B7Z4H4 Q86UL8 Q9Y4G8
PDB IDs 1UEP 1UEQ 1UEW 1UJV 1WFV 6QDT
Enriched GO Terms of Interacting Partners?
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