PLEKHM1 and MUC2

Number of citations of the paper that reports this interaction (PubMedID 12820725)
1

Data Source:
HPRD (in vitro)

		PLEKHM1	MUC2
Description		pleckstrin homology and RUN domain containing M1	mucin 2, oligomeric mucus/gel-forming
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Lysosome Lysosomal Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle Autolysosome	Extracellular Space Golgi Lumen Plasma Membrane Extracellular Matrix Collagen-containing Extracellular Matrix Inner Mucus Layer Outer Mucus Layer
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Protein Transport Lysosome Localization Intracellular Signal Transduction Positive Regulation Of Bone Resorption Autophagosome-lysosome Fusion Positive Regulation Of Ruffle Assembly Late Endosome To Lysosome Transport	Maintenance Of Gastrointestinal Epithelium
Pathways
Drugs
Diseases
GWAS		Alcohol use disorder (total score) ( 30336701) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 28093568) Cortical volume ( 32963231) Daytime nap ( 33568662) Epithelial ovarian cancer ( 25581431) Hip circumference ( 28552196) Liver enzyme levels (alkaline phosphatase) ( 33972514) Male-pattern baldness ( 29146897 28196072) Monocyte count ( 32888494) Neuroticism ( 29255261) Parkinson's disease ( 20070850) Remission after SSRI treatment in MDD or neuroticism ( 29559929)	Asthma ( 31361310 31959851 30929738 34103634 32296059) Asthma (adult onset) ( 30929738) Interstitial lung disease ( 23583980) Medication use (adrenergics, inhalants) ( 31015401)
Interacting Genes		10 interacting genes: BID CTDSP1 EIF2S2 GADD45G MAPK6 MOB4 MUC2 PAFAH1B3 SERPINB9 TRIM54	5 interacting genes: GALNT12 GALNT14 MLH1 NUP98 PLEKHM1
Entrez ID		9842	4583
HPRD ID		11439	11828
Ensembl ID		ENSG00000225190	ENSG00000198788
Uniprot IDs		Q9Y4G2
PDB IDs		5DPR 5DPS 5DPT 5DPW
Enriched GO Terms of Interacting Partners?
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