SPATA2 and CEP72

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
HPRD (two hybrid)

		SPATA2	CEP72
Description		spermatogenesis associated 2	centrosomal protein 72
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Cytoplasm	Centrosome Cytosol Centriolar Satellite
	Molecular Function	Protein Binding Signaling Receptor Complex Adaptor Activity Protein-containing Complex Binding Ubiquitin-specific Protease Binding	Protein Binding
	Biological Process	Spermatogenesis Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Inflammatory Response Regulation Of Necroptotic Process Necroptotic Process Protein K63-linked Deubiquitination Seminiferous Tubule Development Protein Linear Deubiquitination	Spindle Organization Centriole Replication Gamma-tubulin Complex Localization Regulation Of Protein Localization To Centrosome
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Gut microbiota (beta diversity) ( 27723756) Psoriasis ( 20953189 25574825 18364390)	Barrett's esophagus or Esophageal adenocarcinoma ( 27527254 32918910) Barrett's esophagus or esophageal adenocarcinoma x sex interaction (2df test) ( 32918910) Esophageal adenocarcinoma ( 27527254) Lung disease severity in cystic fibrosis ( 26417704) Obesity-related traits ( 23251661) Ulcerative colitis ( 28067908 20228799) Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia ( 25710658)
Interacting Genes		22 interacting genes: ANKRD11 APP ATP6V1H C2CD6 CCDC102B CEP72 DUT EFHC1 GOLGA2 GPANK1 KAT5 KIFC3 LENG1 MAD1L1 OTULIN PTPN6 RNF31 TBC1D22B TNIP1 TRAF2 TRIM27 ZNF835	26 interacting genes: ATXN7 CATIP CHCHD3 FAM161A FAM90A1 FXR1 GOLGA6L9 IGHM IL16 INCA1 KIAA0408 LNX1 MCM10 NME7 PCM1 PIN4 PSMA1 SHANK3 SMARCA2 SPATA2 SPATA24 SRSF2 STAMBPL1 ZBTB16 ZNF417 ZNF688
Entrez ID		9825	55722
HPRD ID		09636	07685
Ensembl ID		ENSG00000158480	ENSG00000112877
Uniprot IDs		A8K0S9 B4DID4 Q9UM82	Q9P209
PDB IDs		5LJM 5LJN
Enriched GO Terms of Interacting Partners?
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