RNF40 and GRIN2A

RNF40

GRIN2A

Description ring finger protein 40 glutamate ionotropic receptor NMDA type subunit 2A
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Immunoglobulin light chain (AL) amyloidosis ( 28025584)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Bipolar disorder ( 33263727 31043756)
  • Bipolar I disorder ( 31043756)
  • Chronic kidney disease ( 26420894)
  • Clostridioides difficle infection ( 33841421)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Copper levels ( 26025379)
  • Daytime nap ( 33568662)
  • FEV1 ( 30804560)
  • General risk tolerance (MTAG) ( 30643258)
  • Hallux valgus ( 32131869)
  • Hepatitis B ( 22004137)
  • Laryngeal squamous cell carcinoma ( 25194280)
  • Lung function (FVC) ( 30804560)
  • Metabolite levels ( 23823483)
  • Night sleep phenotypes ( 27126917)
  • Refractive error ( 32231278)
  • Rosacea symptom severity ( 29771307)
  • Schizophrenia ( 28991256 25056061 29483656 30285260)
  • Tenofovir clearance in HIV infection ( 26148204)
  • Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
  • Waist circumference adjusted for BMI (smoking interaction) ( 28443625)
Interacting Genes 27 interacting genes: AMOTL2 ATM CCDC146 CDC73 DISC1 DUSP29 EEF1D GRIN2A ITSN1 KIF11 MEOX2 MSL1 MTNR1B NCBP1 NINL RB1 RNF20 SFR1 TRIM51 UBE2A UBE2B UBE2D2 UBE2E1 UBE2I UBE2L6 ZCCHC12 ZNF451 41 interacting genes: ACOT8 ACTN1 AKT1 AP1M1 AP2M1 AP4M1 ARHGAP32 CAMK2A CAMK2B CARHSP1 CASK CDK5 CSNK2A1 CSNK2A2 CSNK2B DLG1 DLG2 DLG3 DLG4 DLGAP1 EML1 FYN GRIN1 GRIN2B GRIN3A GRIN3B ID4 IL16 NEDD4 PATJ PCDH8 PLA2G10 PLCG1 PRKCA PRM1 PTK2B PTPN4 RGS3 RNF40 SPTAN1 SRC
Entrez ID 9810 2903
HPRD ID 07411 00698
Ensembl ID ENSG00000103549 ENSG00000183454
Uniprot IDs A8K6K1 O75150 A0A6Q8PGD2 Q12879 Q547U9 Q59EW6
PDB IDs 3NFL 5H8F 5H8H 5H8N 5H8Q 5I2K 5I2N 5KCJ 5KDT 5TP9 5TPA 6IRA 6IRF 6IRG 6IRH
Enriched GO Terms of Interacting Partners?
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