IP6K1 and UBE4A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		IP6K1	UBE4A
Description		inositol hexakisphosphate kinase 1	ubiquitination factor E4A
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cytosol	Ubiquitin Ligase Complex Nucleus Cytoplasm
	Molecular Function	Inositol-1,3,4,5,6-pentakisphosphate Kinase Activity Inositol Hexakisphosphate Kinase Activity Inositol Heptakisphosphate Kinase Activity Inositol Hexakisphosphate 5-kinase Activity Protein Binding ATP Binding Kinase Activity Inositol Hexakisphosphate 1-kinase Activity Inositol Hexakisphosphate 3-kinase Activity Inositol 5-diphosphate Pentakisphosphate 5-kinase Activity Inositol Diphosphate Tetrakisphosphate Kinase Activity	Protein Binding Ubiquitin-ubiquitin Ligase Activity
	Biological Process	Phosphorylation Inositol Phosphate Biosynthetic Process Inositol Phosphate Metabolic Process Phosphatidylinositol Phosphate Biosynthetic Process Negative Regulation Of Cold-induced Thermogenesis	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent ERAD Pathway
Pathways		Synthesis of pyrophosphates in the cytosol Synthesis of IPs in the nucleus	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Diastolic blood pressure ( 27841878) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Hand grip strength ( 29691431) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip index ( 34021172) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 23128233) Intelligence (MTAG) ( 29326435) Parental longevity (mother's age at death or mother's attained age) ( 31484785) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Resting heart rate ( 29769521 27798624) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 27841878) Ulcerative colitis ( 25082827) Visceral adipose tissue volume ( 34128465)	Celiac disease and Rheumatoid arthritis ( 26546613) Fat distribution (HIV) ( 21897333)
Interacting Genes		12 interacting genes: ADAMTSL4 CACNA1A CLK1 COPS2 DDB1 EXOSC7 GPS1 PICK1 RAB3IL1 RPL11 UBE4A VIM	14 interacting genes: CASP6 EPHA2 GZMB IP6K1 MAVS PTTG1 RSAD2 SC5D SLA UBE2D1 UBE2D2 UBE2D3 UBE2D4 VCP
Entrez ID		9807	9354
HPRD ID		07379	06793
Ensembl ID		ENSG00000176095	ENSG00000110344
Uniprot IDs		A0A024R2X2 Q92551	Q14139
PDB IDs			1WGM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?