PHYHIP and HDAC11

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PHYHIP	HDAC11
Description		phytanoyl-CoA 2-hydroxylase interacting protein	histone deacetylase 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Histone Deacetylase Complex Nucleus Plasma Membrane
	Molecular Function	Protein Tyrosine Kinase Binding	Histone Deacetylase Activity Protein Binding NAD-dependent Histone Deacetylase Activity (H3-K14 Specific) DNA-binding Transcription Factor Binding
	Biological Process	Protein Localization	Chromatin Organization Oligodendrocyte Development Histone Deacetylation Histone H3 Deacetylation
Pathways			NOTCH1 Intracellular Domain Regulates Transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Notch-HLH transcription pathway
Drugs			Belinostat Panobinostat
Diseases
GWAS		Hypertriglyceridemia ( 23505323)	Body mass index ( 26426971) Height ( 20881960) Hip circumference adjusted for BMI ( 34021172 25673412) Ulcerative colitis ( 26278503) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		24 interacting genes: ADGRB1 COPS6 DYRK1A EEF1A1 ERG28 FAM131A HDAC11 HNRNPA1 MAGED4B MED8 METTL18 NDRG1 NDUFV3 NFE2 PHYH PNPLA2 PPIE PRMT5 S100A13 SMARCC2 SUPT5H TTR WDR89 ZZEF1	9 interacting genes: CDC25A CDKN1A HDAC6 MAPK6 MRPS25 NELFCD NRM NUP210 PHYHIP
Entrez ID		9796	79885
HPRD ID		16345	09146
Ensembl ID		ENSG00000168490	ENSG00000163517
Uniprot IDs		Q92561	B5MCQ6 E7ETT9 Q6IA14 Q96DB2
PDB IDs
Enriched GO Terms of Interacting Partners?
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