KIAA0586 and DACT1

		KIAA0586	DACT1
Description		KIAA0586	dishevelled binding antagonist of beta catenin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Inner Segment Cytoplasm Centrosome Centriole Ciliary Basal Body	Nucleus Nucleoplasm Cytoplasm Cytosol Synapse
	Molecular Function		Protein Kinase C Binding Protein Binding Beta-catenin Binding Histone Deacetylase Binding Protein Kinase A Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Delta-catenin Binding
	Biological Process	Smoothened Signaling Pathway Cilium Assembly Regulation Of Establishment Of Protein Localization	Negative Regulation Of Transcription By RNA Polymerase II Wnt Signaling Pathway Neural Tube Development Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Regulation Of Protein Stability Negative Regulation Of Protein Binding Positive Regulation Of Protein Binding Positive Regulation Of Protein Catabolic Process Negative Regulation Of JNK Cascade Embryonic Hindgut Morphogenesis Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway Regulation Of Nodal Signaling Pathway Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Beta-catenin-TCF Complex Assembly Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways			Degradation of DVL
Drugs
Diseases
GWAS		Body mass index ( 28552196) Brain morphology (MOSTest) ( 32665545) Cortical surface area ( 32963231) Cortical thickness ( 32963231) Cortical volume ( 32963231) Metabolite levels ( 23823483) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Brain morphology (MOSTest) ( 32665545) Colorectal cancer or advanced adenoma ( 30510241) Dentate gyrus granule cell layer volume (corrected for total hippocampal volume) ( 30279459) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hippocampal subfield CA1 volume (corrected for total hippocampal volume) ( 30279459) Hippocampal tail volume (corrected for total hippocampal volume) ( 30279459) Leftâ€“right brain asymmetry ( 33723403) Metabolite levels ( 23823483) Occipital lobe volume ( 31396565) Parietal lobe volume ( 31396565)
Interacting Genes		6 interacting genes: DAAM1 DACT1 EXOC5 RTN1 TSC22D2 UBC	7 interacting genes: APPL1 C7orf25 CSNK2B KIAA0586 PPP1CC SH3GL2 TK1
Entrez ID		9786	51339
HPRD ID		11092	09709
Ensembl ID		ENSG00000100578	ENSG00000165617
Uniprot IDs		A0A087WYM5 A0A494C171 B4DYW5 B7Z7W7 Q9BVV6	Q9NYF0
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?