ZNF536 and C19orf12

		ZNF536	C19orf12
Description		zinc finger protein 536	chromosome 19 open reading frame 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Mitochondrion Endoplasmic Reticulum Cytosol Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Retinoic Acid-responsive Element Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Negative Regulation Of Neuron Differentiation Negative Regulation Of Retinoic Acid Receptor Signaling Pathway	Autophagy Apoptotic Process Response To Oxidative Stress Mitochondrial Calcium Ion Homeostasis
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs) ( 23648065) Age-related hearing impairment ( 24939585) Atorvastatin-induced myopathy ( 31220337) Body mass index ( 28892062 25673413) Body size at age 10 ( 32376654) Cerebrospinal P-tau181p levels ( 28247064) Chin dimples ( 27182965) Chronotype ( 30696823) Falling risk ( 32999390) General risk tolerance (MTAG) ( 30643258) High density lipoprotein cholesterol levels ( 34074324) Major depressive disorder ( 27479909) Myocardial infarction in hypertension (calcium channel blocker interaction) ( 26516778) Myopia (pathological) ( 23049088) Obesity-related traits ( 23251661) Remission after SSRI treatment in major depression ( 30034349) Schizophrenia ( 28991256 25056061 29483656 30285260) Select biomarker traits ( 17903293) Severe malaria ( 29381699) Severe malaria (adjusted for sickle cell variant rs334) ( 29381699) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for body mass index ( 27195708)	Body mass index ( 26426971) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Height ( 28552196) Response to fenofibrate (total cholesterol levels) ( 27002377)
Interacting Genes		3 interacting genes: C19orf12 POLR2I TSHZ3	3 interacting genes: APP IKBKG ZNF536
Entrez ID		9745	83636
HPRD ID		15825	12696
Ensembl ID		ENSG00000198597	ENSG00000131943
Uniprot IDs		O15090	Q9NSK7
PDB IDs
Enriched GO Terms of Interacting Partners?
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