RIMS2 and RPH3AL

Number of citations of the paper that reports this interaction (PubMedID 10707984)
81

Data Source:
HPRD (in vivo, two hybrid)

		RIMS2	RPH3AL
Description		regulating synaptic membrane exocytosis 2	rabphilin 3A like (without C2 domains)
Image			No pdb structure
GO Annotations	Cellular Component	Presynaptic Membrane Cell Projection Presynaptic Active Zone Cytoskeleton Of Presynaptic Active Zone Extracellular Exosome	Cytoplasm Transport Vesicle Membrane Secretory Granule Membrane
	Molecular Function	Protein Binding Small GTPase Binding Transmembrane Transporter Binding Metal Ion Binding	Protein Binding Cytoskeletal Protein Binding LIM Domain Binding Small GTPase Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Positive Regulation Of Gene Expression Calcium-ion Regulated Exocytosis Regulation Of Exocytosis CAMP-mediated Signaling Insulin Secretion Cell Differentiation Regulation Of Membrane Potential Regulation Of Synaptic Plasticity Calcium Ion-regulated Exocytosis Of Neurotransmitter Positive Regulation Of Synaptic Transmission Spontaneous Neurotransmitter Secretion Positive Regulation Of Inhibitory Postsynaptic Potential Positive Regulation Of Dendrite Extension Positive Regulation Of Excitatory Postsynaptic Potential	Intracellular Protein Transport Exocytosis Response To Xenobiotic Stimulus Regulation Of Exocytosis Positive Regulation Of Protein Secretion
Pathways
Drugs
Diseases
GWAS		Cocaine dependence ( 23958962) Dietary fat liking ( 32516399) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) High density lipoprotein cholesterol levels ( 30498476) Monoclonal gammopathy of undetermined significance ( 30737484) Multiple system atrophy (pathologically confirmed) ( 27629089) Parkinson's disease progression (cognitive) ( 33958783)	AIDS progression ( 21502085) Dimensional psychopathology (Cognitive) ( 29496196) Idiopathic intracranial hypertension ( 29608535) Impaired insulin sensitivity in response to n-3 PUFA supplementation ( 31779001)
Interacting Genes		14 interacting genes: ABCA1 CACNA1S CD44 PABPC1 RAB27A RAB3A RAB3B RAB3C RAB3D RAB8A RABAC1 RAPGEF4 RPH3AL YWHAH	25 interacting genes: ANKRD11 ATPAF2 C1orf109 HNRNPK KHDRBS3 MID2 MYO15B PNMA3 PRKAB2 PSME3 RAB27A RAB27B RAB3A RAB3B RAB3C RAB3D RAB3GAP1 RAB8A RIMS2 RSPH14 SAAL1 SCNM1 TCEA3 UNC13B ZYX
Entrez ID		9699	9501
HPRD ID		09436	05345
Ensembl ID		ENSG00000176406	ENSG00000181031
Uniprot IDs		Q9UQ26	A8K7D5 Q9UNE2
PDB IDs		1V27 1WFG
Enriched GO Terms of Interacting Partners?
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