TGS1 and ANKRD28

Number of citations of the paper that reports this interaction (PubMedID 23414517)
13

Data Source:
BioGRID (two hybrid)

		TGS1	ANKRD28
Description		trimethylguanosine synthase 1	ankyrin repeat domain 28
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Cajal Body Small Nuclear Ribonucleoprotein Complex	Nucleoplasm Cytosol
	Molecular Function	Protein Binding RNA Methyltransferase Activity RNA Trimethylguanosine Synthase Activity	Protein Binding
	Biological Process	Spliceosomal SnRNP Assembly 7-methylguanosine RNA Capping Ribonucleoprotein Complex Biogenesis 7-methylguanosine Cap Hypermethylation
Pathways		RORA activates gene expression BMAL1:CLOCK,NPAS2 activates circadian gene expression snRNP Assembly PPARA activates gene expression PPARA activates gene expression Transcriptional activation of mitochondrial biogenesis Activation of gene expression by SREBF (SREBP) Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by PPARalpha Circadian Clock Cytoprotection by HMOX1 Heme signaling	Telomere Extension By Telomerase COPII-mediated vesicle transport
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa) ( 27723756) Height ( 18391951) Serum thyroid-stimulating hormone levels ( 24852370)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Mean platelet volume ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252) Refractive error ( 32231278)
Interacting Genes		9 interacting genes: ANKRD28 COIL CREBBP EED EP300 HNF4A NCOA6 NOXA1 ZNF76	34 interacting genes: ABCF2 AGPAT2 ANK2 ANKRD26 ANKRD50 BCL3 BRCA1 CCDC187 CD164 CSNK2B EEF1G EHMT2 EIF3D GADD45GIP1 HNRNPK HNRNPR INCA1 KCNV2 MYOM1 NOTCH2 NOTCH3 PIBF1 PTRH1 RNF11 TGM2 TGS1 THAP7 TMIE TNKS TNKS2 TTN UACA YTHDC1 ZNF512B
Entrez ID		96764	23243
HPRD ID		07567	10651
Ensembl ID		ENSG00000137574	ENSG00000206560
Uniprot IDs		Q96RS0	A0A024R2I9 O15084
PDB IDs		3EGI 3GDH
Enriched GO Terms of Interacting Partners?
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