IQCB1 and NECTIN3

		IQCB1	NECTIN3
Description		IQ motif containing B1	nectin cell adhesion molecule 3
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Nucleoplasm Centrosome Centriole Cytosol Cilium Microtubule Cytoskeleton Photoreceptor Connecting Cilium Intercellular Bridge Extracellular Exosome Mitotic Spindle	Plasma Membrane Cell-cell Junction Adherens Junction Axon Dendrite Apical Junction Complex Cell-cell Contact Zone Hippocampal Mossy Fiber To CA3 Synapse Integral Component Of Postsynaptic Density Membrane
	Molecular Function	Protein Binding Calmodulin Binding Enzyme Binding	Protein Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding
	Biological Process	Photoreceptor Cell Maintenance Maintenance Of Animal Organ Identity Cilium Assembly	Lens Morphogenesis In Camera-type Eye Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Spermatid Development Fertilization Retina Morphogenesis In Camera-type Eye Establishment Of Protein Localization To Plasma Membrane Protein Localization To Cell Junction
Pathways		Anchoring of the basal body to the plasma membrane	Adherens junctions interactions Nectin/Necl trans heterodimerization
Drugs
Diseases
GWAS		Hemoglobin levels ( 32327693) Multiple sclerosis ( 31604244 24076602) Multiple sclerosis and triglyceride levels (pleiotropy) ( 26920376)	Feeling hurt ( 29500382)
Interacting Genes		18 interacting genes: CALM2 CALML3 CD80 KIF9 LDOC1 LMOD1 MARCHF7 MNS1 NECTIN3 PCMT1 PDE9A SESTD1 SMARCD1 SPG21 TBL1X TRH TRIM32 UPK1B	23 interacting genes: AFDN CYSRT1 IQCB1 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-1 KRTAP4-2 KRTAP5-11 KRTAP5-9 KRTAP9-3 NBPF19 NECTIN1 NECTIN2 NOTCH2NLA OTX1 PARD3 PVR RGS20 TIGIT
Entrez ID		9657	25945
HPRD ID		11049	08454
Ensembl ID		ENSG00000173226	ENSG00000177707
Uniprot IDs		Q15051	Q9NQS3
PDB IDs			4FOM
Enriched GO Terms of Interacting Partners?
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