GCC2 and ARL1

Number of citations of the paper that reports this interaction (PubMedID 12972563)
53

Data Source:
BioGRID (two hybrid)

		GCC2	ARL1
Description		GRIP and coiled-coil domain containing 2	ADP ribosylation factor like GTPase 1
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GO Annotations	Cellular Component	Nucleoplasm Golgi Apparatus Trans-Golgi Network Cytosol Membrane	Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Trans-Golgi Network Membrane
	Molecular Function	Protein Binding Small GTPase Binding Identical Protein Binding	GTPase Activity Protein Binding GTP Binding Enzyme Activator Activity Protein Domain Specific Binding Metal Ion Binding
	Biological Process	Protein Targeting To Lysosome Microtubule Organizing Center Organization Protein Localization To Golgi Apparatus Microtubule Anchoring Late Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Regulation Of Protein Exit From Endoplasmic Reticulum Recycling Endosome To Golgi Transport Golgi Ribbon Formation	Intracellular Protein Transport Golgi Organization Toxin Metabolic Process Vesicle-mediated Transport Activation Of Phospholipase D Activity Protein Localization To Golgi Apparatus Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport
Pathways		Retrograde transport at the Trans-Golgi-Network Signaling by ALK fusions and activated point mutants	Retrograde transport at the Trans-Golgi-Network
Drugs			Guanosine-5'-Diphosphate
Diseases
GWAS		Excessive hairiness ( 29895819) Eyebrow thickness ( 26926045) Liver enzyme levels (alkaline phosphatase) ( 33972514) Low density lipoprotein cholesterol levels ( 32154731) Mean platelet volume ( 27863252) Platelet distribution width ( 32888494)	Lung cancer in never smokers ( 28604730) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
Interacting Genes		7 interacting genes: ARL1 ICAM3 POU2AF1 RANBP2 SPOP SRPK2 SULT1C3	8 interacting genes: ARFIP2 COPG2 DRD2 GCC1 GCC2 GOLGA1 GOLGA4 SCOC
Entrez ID		9648	400
HPRD ID		11001	04574
Ensembl ID		ENSG00000135968	ENSG00000120805
Uniprot IDs		B3KR21 Q8IWJ2	B4DZG7 P40616
PDB IDs		3BBP	1UPT 4DCN 5EE5 5J5C
Enriched GO Terms of Interacting Partners?
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