SEC24C and WIPF1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		SEC24C	WIPF1
Description		SEC24 homolog C, COPII coat complex component	WAS/WASL interacting protein family member 1
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GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat Endoplasmic Reticulum Exit Site	Ruffle Cytosol Actin Filament Actin Cytoskeleton Cytoplasmic Vesicle
	Molecular Function	SNARE Binding Protein Binding Zinc Ion Binding	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding
	Biological Process	In Utero Embryonic Development Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport COPII-coated Vesicle Cargo Loading	Actin Polymerization Or Depolymerization Actin Filament-based Movement Protein-containing Complex Assembly
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs CDC42 GTPase cycle RAC1 GTPase cycle FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Crohn's disease ( 28067908) Self-rated health ( 27864402)	Atrial fibrillation ( 30061737 29892015) Mean platelet volume ( 32888494) Platelet distribution width ( 32888494) Pulse pressure ( 27841878) Resting heart rate ( 27798624) Systolic blood pressure ( 27841878) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		9 interacting genes: APP FBXO7 MIA2 MIA3 MOS SEC23A SEC23B SPP1 WIPF1	27 interacting genes: ABI2 ACTC1 ACTG1 ALAS1 APBB1 CACNG2 CDC42 CRKL CTTN FASTK GRB2 HCK HLCS HOMER3 ITSN2 NCK1 NCK2 PRKCQ PRPF40A RER1 SEC24C SH3RF1 WAS WASL WBP4 WWP2 ZAP70
Entrez ID		9632	7456
HPRD ID		06217	03835
Ensembl ID		ENSG00000176986	ENSG00000115935
Uniprot IDs		A0A024QZM6 P53992	A0A140VJZ9 O43516 Q2YDC4
PDB IDs		3EH2 6PU1	2A41
Enriched GO Terms of Interacting Partners?
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