TCL1B and LSM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TCL1B	LSM1
Description		TCL1 family AKT coactivator B	LSM1 homolog, mRNA degradation associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Protein-containing Complex	P-body Nucleus Cytoplasm Cytosol Axon Dendrite Neuronal Cell Body Messenger Ribonucleoprotein Complex Lsm1-7-Pat1 Complex
	Molecular Function	Protein Binding Protein Kinase Binding Protein Serine/threonine Kinase Activator Activity	RNA Cap Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding
	Biological Process	Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Protein Serine/threonine Kinase Activity	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Metabolic Process Stem Cell Population Maintenance Negative Regulation Of Neuron Differentiation Histone MRNA Catabolic Process
Pathways			mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 22037555 29483656)
Interacting Genes		17 interacting genes: AKT1 AKT2 APP BAG4 EFCAB2 GLRX3 LSM1 LSM5 LSM7 MARK1 MEIS3 MKRN3 PLEKHA3 PNMA1 SNRPG TNPO2 ZNF330	34 interacting genes: AGR2 AGR3 BEX5 CLIC1 DAPL1 EXOSC6 EXOSC8 GLUD1 GOLGA7 GRHPR GSTA4 HSP90AA1 LSM2 LSM3 LSM5 LSM6 LSM7 MCCD1 MPDU1 N4BP1 NARS1 NDUFAF3 NSD3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TCL1B TFCP2 TMEM214 UPF2 UXT VPS11
Entrez ID		9623	27257
HPRD ID		04795	06281
Ensembl ID		ENSG00000213231	ENSG00000175324
Uniprot IDs		A0A024R6P4 O95988	A0A0S2Z590 O15116
PDB IDs
Enriched GO Terms of Interacting Partners?
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