CD47 and IGSF8

		CD47	IGSF8
Description		CD47 molecule	immunoglobulin superfamily member 8
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane	Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Binding Thrombospondin Receptor Activity Protein Binding Involved In Heterotypic Cell-cell Adhesion Cell-cell Adhesion Mediator Activity	Protein Binding
	Biological Process	Integrin-mediated Signaling Pathway Positive Regulation Of Cell Population Proliferation Cell Migration Positive Regulation Of Cell-cell Adhesion Regulation Of Interferon-gamma Production Regulation Of Interleukin-10 Production Regulation Of Interleukin-12 Production Regulation Of Interleukin-6 Production Regulation Of Tumor Necrosis Factor Production Heterotypic Cell-cell Adhesion Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Inflammatory Response Positive Regulation Of Phagocytosis Positive Regulation Of T Cell Activation Positive Regulation Of Stress Fiber Assembly Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Interleukin-12 ATP Export Negative Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Monocyte Extravasation	Single Fertilization Nervous System Development Skeletal Muscle Tissue Development Cell Motility
Pathways		Cell surface interactions at the vascular wall Integrin cell surface interactions Signal regulatory protein family interactions Signal regulatory protein family interactions Neutrophil degranulation
Drugs
Diseases
GWAS		Bipolar disorder ( 33263727 31043756) Body mass index ( 25673413) Refractive error ( 32231278) Regular attendance at a religious group ( 29970889)
Interacting Genes		24 interacting genes: BNIP3 EPB42 FAS GAP43 GNAI1 IGF2BP2 IGSF8 ITGAV MAP3K10 MTIF3 MUC1 P2RY2 PLA1A PTK2 PVR RHAG SIRPA SYNE4 TAGLN3 TFEB THBS1 TMEM167B UBQLN1 ZBTB20	18 interacting genes: A2M CD47 CD81 CD82 CD9 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-4 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP4-12 KRTAP5-7 SLIT3 TGM1
Entrez ID		961	93185
HPRD ID		03017	09438
Ensembl ID		ENSG00000196776	ENSG00000162729
Uniprot IDs		A0A0A1TSG4 Q08722	Q969P0
PDB IDs		2JJS 2JJT 2VSC 4CMM 4KJY 5IWL 5TZ2 5TZT 5TZU
Enriched GO Terms of Interacting Partners?
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