CD44 and TGFBR2

  • Number of citations of the paper that reports this interaction (PubMedID 12145287)
  • 79
  • Data Source:
  • HPRD (in vivo)

CD44

TGFBR2

Description CD44 molecule (Indian blood group) transforming growth factor beta receptor 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Breast cancer ( 29059683 23535729)
  • Cellular nuclear factor (erythroid-derived 2)-like 2 levels ( 30767168)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Estimated glomerular filtration rate ( 31152163)
  • Heel bone mineral density ( 30598549)
  • Metabolite levels ( 23823483)
  • Migraine ( 22683712 27322543)
  • Migraine - clinic-based ( 23793025)
  • Night sleep phenotypes ( 27126917)
  • Postprandial triglyceride response ( 32603185)
  • Response to chemotherapy in breast cancer hypertensive cases (cumulative dose) (bevacizumab) ( 25117820)
  • Systolic blood pressure ( 30224653)
  • Tonometry ( 17903302)
Interacting Genes 70 interacting genes: ABCB5 AKT1 ANK1 ARHGEF1 ARHGEF12 ARNT BDNF CAT CCND2 CD4 CD74 CDK4 CDK6 CDKN2A CDKN2B COL14A1 COL1A1 COL1A2 CSK CSTF3 DMP1 DPT EGFR EPB41 EPHA2 ERBB2 ERBB4 EZR FGF2 FGFR4 FN1 FYN GARS1 GLIS2 GRM1 HBEGF HMMR IGFBP3 KDELR2 LATS2 LCK LMO2 MADCAM1 MAP2K3 MAP2K5 MAP3K13 MDM4 MET MMP1 MMP7 MMP9 MSN NF2 NONO PDGFRA PKN1 RAF1 RIMS2 SELE SPP1 SRC SRD5A1 SRGN STK11 TGFBR1 TGFBR2 TIAM1 VAV2 VCAN VHL 50 interacting genes: ACVR1 ACVRL1 AP2B1 APP ARHGEF6 ARHGEF7 CCNB1 CCNB2 CD44 CDK1 CLU CTNNB1 DAB2 DAXX DYNLT4 EIF3I ENG FANCC GOPC KCNK18 MAP2K1 NRP1 OSR1 PAK1 PDGFRA PIK3R1 PIK3R2 PML PPP2CB PSMD14 RCVRN SMAD3 SMAD4 SMAD7 SNX6 STRAP TDGF1 TERT TGFB1 TGFB1I1 TGFB2 TGFB3 TGFBR1 TGFBR3 TGFBRAP1 TRAP1 TRMO TSSK1B ZFYVE9 ZNF510
Entrez ID 960 7048
HPRD ID 00115 01823
Ensembl ID ENSG00000026508 ENSG00000163513
Uniprot IDs P16070 A3QNQ0 D2JYI1 P37173
PDB IDs 1POZ 1UUH 2I83 4PZ3 4PZ4 6TXS 1KTZ 1M9Z 1PLO 2PJY 3KFD 4P7U 4XJJ 5E8V 5E8Y 5E91 5E92 5QIN 5TX4 5TY4
Enriched GO Terms of Interacting Partners?
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