GABBR2 and SPIN1

		GABBR2	SPIN1
Description		gamma-aminobutyric acid type B receptor subunit 2	spindlin 1
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane G Protein-coupled Receptor Heterodimeric Complex Neuron Projection Postsynaptic Membrane GABA Receptor Complex	Nucleus Nucleoplasm Nucleolus Cytosol Nuclear Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled GABA Receptor Activity Protein Binding Protein Heterodimerization Activity	Protein Binding Methylated Histone Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Gamma-aminobutyric Acid Signaling Pathway Chemical Synaptic Transmission Neuron-glial Cell Signaling	Chromatin Organization Regulation Of Transcription, DNA-templated Gamete Generation RRNA Transcription Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of Transcription, DNA-templated Meiotic Cell Cycle
Pathways		Activation of G protein gated Potassium channels G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors) GABA B receptor activation Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs		Baclofen gamma-Aminobutyric acid SGS-742 Arbaclofen Arbaclofen Placarbil
Diseases
GWAS		Gynecologic disease (multivariate analysis) ( 31488892) High chromosomal aberration frequency (chromatid type) ( 31586183) Post-traumatic stress disorder (asjusted for relatedness) ( 23726511) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962) Response to simvastatin treatment (PCSK9 protein level change) ( 25089948) Response to TNF inhibitor in rheumatoid arthritis (change in tender 28-joint count) ( 30166627) Schizophrenia ( 30285260) Systolic blood pressure change trajectory ( 27980656)	Height ( 20881960 31562340 18391951) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		16 interacting genes: ATF4 ATF5 DRD2 GABBR1 GADD45G GLP1R HTR1A KCTD12 KCTD16 NSF RFXAP SAP30 SH3GL3 SPIN1 SPTLC1 TAMALIN	6 interacting genes: GABBR2 HMGB1 HSPB1 PRMT6 PTN RPL5
Entrez ID		9568	10927
HPRD ID		09552	18096
Ensembl ID		ENSG00000136928	ENSG00000106723
Uniprot IDs		H9NIL8 O75899	A0A024R297 Q9Y657
PDB IDs		4F11 4F12 4MQE 4MQF 4MR7 4MR8 4MR9 4MRM 4MS1 4MS3 4MS4 4PAS 6M8R 6OCP 6UO8 6UO9 6UOA 6VJM 6W2X 6WIV 7C7Q 7C7S 7CA3 7CA5 7CUM	2NS2 4H75 4MZF 4MZG 4MZH 5JSG 5JSJ 5Y5W 6I8B 6I8L 6I8Y 6QPL 7BQZ 7BU9 7CNA
Enriched GO Terms of Interacting Partners?
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