BAG2 and CCAR2

Number of citations of the paper that reports this interaction (PubMedID 22365833)
163

Data Source:
BioGRID (two hybrid, two hybrid)

		BAG2	CCAR2
Description		BAG cochaperone 2	cell cycle and apoptosis regulator 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Microtubule Axon Dendrite Chaperone Complex Dendritic Microtubule	Chromatin Nucleus Nucleoplasm Cytoplasm Mitochondrial Matrix Spindle DBIRD Complex
	Molecular Function	Adenyl-nucleotide Exchange Factor Activity Protein Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Transmembrane Transporter Binding Tau Protein Binding Chaperone Binding	RNA Polymerase II Complex Binding RNA Binding Enzyme Inhibitor Activity Protein Binding Enzyme Binding Nuclear Receptor Coactivator Activity
	Biological Process	Protein Folding Positive Regulation Of Protein Processing Protein Metabolic Process Negative Regulation Of Protein Ubiquitination Negative Regulation Of Protein Binding Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin Protein Ligase Activity	Regulation Of Transcription, DNA-templated MRNA Processing Cellular Response To DNA Damage Stimulus Cell Cycle RNA Splicing Response To UV Wnt Signaling Pathway Negative Regulation Of Cell Growth Regulation Of Protein Stability Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of DNA-templated Transcription, Elongation Regulation Of Circadian Rhythm Positive Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Mitochondrial Fragmentation Involved In Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Rhythmic Process Positive Regulation Of Canonical Wnt Signaling Pathway Regulation Of Protein Deacetylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of DNA Damage Checkpoint
Pathways		Regulation of HSF1-mediated heat shock response	Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS			Haemorrhoidal disease ( 33888516)
Interacting Genes		17 interacting genes: CCAR2 DAPK1 DISC1 DNAJC6 HSPA1A HSPA4 HSPA8 LRRK1 LRRK2 MAPKAPK2 MFHAS1 NOTCH3 PINK1 PPIH SLU7 WDR77 WDR83	13 interacting genes: AR BAG2 ELL FMR1 FXR1 FXR2 HTRA2 IKBKB MAILR MYC NLGN3 SUMO2 ZNF335
Entrez ID		9532	57805
HPRD ID		04859	09159
Ensembl ID		ENSG00000112208	ENSG00000158941
Uniprot IDs		O95816	Q8N163
PDB IDs
Enriched GO Terms of Interacting Partners?
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