MPDU1 and LSM1

Number of citations of the paper that reports this interaction (PubMedID 15231747)
57

Data Source:
BioGRID (two hybrid)

		MPDU1	LSM1
Description		mannose-P-dolichol utilization defect 1	LSM1 homolog, mRNA degradation associated
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	P-body Nucleus Cytoplasm Cytosol Axon Dendrite Neuronal Cell Body Messenger Ribonucleoprotein Complex Lsm1-7-Pat1 Complex
	Molecular Function	Protein Binding	RNA Cap Binding RNA Binding MRNA Binding Protein Binding Pre-mRNA Binding
	Biological Process	Protein Folding Dolichol-linked Oligosaccharide Biosynthetic Process Oligosaccharide Biosynthetic Process	Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing RNA Metabolic Process Stem Cell Population Maintenance Negative Regulation Of Neuron Differentiation Histone MRNA Catabolic Process
Pathways		Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective MPDU1 causes MPDU1-CDG (CDG-1f)	mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Hemoglobin levels ( 32327693) IgA nephropathy ( 22197929) Refractive error ( 32231278)	Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 28991256 22037555 29483656)
Interacting Genes		3 interacting genes: LSM1 MANBAL SHBG	34 interacting genes: AGR2 AGR3 BEX5 CLIC1 DAPL1 EXOSC6 EXOSC8 GLUD1 GOLGA7 GRHPR GSTA4 HSP90AA1 LSM2 LSM3 LSM5 LSM6 LSM7 MCCD1 MPDU1 N4BP1 NARS1 NDUFAF3 NSD3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TCL1B TFCP2 TMEM214 UPF2 UXT VPS11
Entrez ID		9526	27257
HPRD ID		04951	06281
Ensembl ID		ENSG00000129255	ENSG00000175324
Uniprot IDs		A0A0S2Z4W8 B4DLH7 J3QW43 O75352	A0A0S2Z590 O15116
PDB IDs
Enriched GO Terms of Interacting Partners?
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