TECR and CLDN5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TECR	CLDN5
Description		trans-2,3-enoyl-CoA reductase	claudin 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Integral Component Of Membrane Apicolateral Plasma Membrane Lateral Plasma Membrane Cell Junction Cortical Actin Cytoskeleton Paranode Region Of Axon Schmidt-Lanterman Incisure Tight Junction
	Molecular Function	Protein Binding Oxidoreductase Activity Very-long-chain-acyl-CoA Dehydrogenase Activity Very-long-chain Enoyl-CoA Reductase Activity	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Sphingolipid Metabolic Process Fatty Acid Elongation Long-chain Fatty-acyl-CoA Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process	Outflow Tract Morphogenesis Cell-cell Junction Assembly Cell Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Learning Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration Positive Regulation Of Protein Binding Maintenance Of Blood-brain Barrier Myelination Negative Regulation Of Vascular Permeability Response To Ethanol Roof Of Mouth Development Face Morphogenesis Bicellular Tight Junction Assembly Tight Junction Assembly Positive Regulation Of Establishment Of Endothelial Barrier Positive Regulation Of Bicellular Tight Junction Assembly Establishment Of Blood-retinal Barrier
Pathways		Synthesis of very long-chain fatty acyl-CoAs	Tight junction interactions RUNX1 regulates expression of components of tight junctions
Drugs
Diseases
GWAS
Interacting Genes		28 interacting genes: ARL13B CD79A CLDN5 CRB3 CREB3 CREB3L1 ELOVL4 ERGIC3 FAM209A FBXO7 GET1 GOLT1A HACD1 JAGN1 MFSD14B MMGT1 MUC1 NOS3 PAXIP1 PGRMC2 PTEN RETREG3 SLC10A6 SLC7A14 STING1 STOM TFAM VMA21	40 interacting genes: AQP1 BTNL8 CCDC167 CLDN3 CLRN2 CNPY3 CORIN CTRL CXCL9 CYB561A3 EFNA5 EHHADH ERG28 ERMP1 FXYD6-FXYD2 GYPA LAT LHFPL5 MIP MPDZ PLP2 PLPPR2 PMP22 RPRM SFTPC SGCG SLC35B4 SMIM3 TECR TF TJP1 TMEM128 TMEM140 TMEM14C TMEM182 TMEM190 TMEM222 TSPAN2 VAMP5 YIPF1
Entrez ID		9524	7122
HPRD ID		17076	03654
Ensembl ID		ENSG00000099797	ENSG00000184113
Uniprot IDs		B3KSQ1 Q9NZ01	D3DX19 O00501
PDB IDs		2DZJ
Enriched GO Terms of Interacting Partners?
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