ADAMTS1 and JAML

		ADAMTS1	JAML
Description		ADAM metallopeptidase with thrombospondin type 1 motif 1	junction adhesion molecule like
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Extracellular Matrix Cytoplasmic Vesicle Collagen-containing Extracellular Matrix	Nucleoplasm Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane
	Molecular Function	Metalloendopeptidase Activity Protein Binding Heparin Binding Metallopeptidase Activity Zinc Ion Binding	Integrin Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding
	Biological Process	Ovulation From Ovarian Follicle Kidney Development Proteolysis Integrin-mediated Signaling Pathway Negative Regulation Of Cell Population Proliferation Negative Regulation Of Angiogenesis Extracellular Matrix Organization Heart Trabecula Formation Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration	Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Neutrophil Chemotaxis Monocyte Extravasation Gamma-delta T Cell Activation Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Neutrophil Extravasation
Pathways		Degradation of the extracellular matrix Defective B3GALTL causes Peters-plus syndrome (PpS) O-glycosylation of TSR domain-containing proteins	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 30820047) Alzheimer's disease or family history of Alzheimer's disease ( 33589840) Blood protein levels ( 28240269) Cerebrospinal fluid neurofilament light levels ( 31930058) Health literacy ( 31250787) Metabolite levels ( 23823483)	Sleep duration (long sleep) ( 30846698)
Interacting Genes		11 interacting genes: A2M ACAN ADRA2B FAM32A FURIN JAML KRT40 KRTAP10-8 TPSAB1 VCAN VEGFA	3 interacting genes: ADAMTS1 CXADR MAL
Entrez ID		9510	120425
HPRD ID		05530	16482
Ensembl ID		ENSG00000154734	ENSG00000160593
Uniprot IDs		B2RB33 Q9UHI8	B3KUI3 Q496M4 Q86YT9
PDB IDs		2JIH 2V4B 3Q2G 3Q2H
Enriched GO Terms of Interacting Partners?
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