SCARB2 and GPR37L1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SCARB2	GPR37L1
Description		scavenger receptor class B member 2	G protein-coupled receptor 37 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosomal Membrane Endoplasmic Reticulum Membrane Plasma Membrane Focal Adhesion Endosome Membrane Membrane Integral Component Of Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Late Endosome Membrane Lysosomal Lumen Extracellular Exosome	Plasma Membrane Integral Component Of Membrane Receptor Complex Ciliary Membrane
	Molecular Function	Virus Receptor Activity Phosphatidylserine Binding Transmembrane Signaling Receptor Activity Scavenger Receptor Activity Protein Binding Cholesterol Binding Enzyme Binding Phosphatidylcholine Binding Cargo Receptor Activity Protein Homodimerization Activity Chaperone Binding	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Prosaposin Receptor Activity Peptide Binding
	Biological Process	Protein Targeting To Lysosome Receptor-mediated Endocytosis Sensory Perception Of Sound Gene Expression Positive Regulation Of Neuron Projection Development Aminophospholipid Transport Regulation Of Cellular Carbohydrate Catabolic Process Viral Entry Into Host Cell Regulation Of Endosome Organization Regulation Of Glucosylceramidase Activity Regulation Of Lysosome Organization	Negative Regulation Of Systemic Arterial Blood Pressure Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cerebellar Granule Cell Precursor Proliferation Positive Regulation Of MAPK Cascade Negative Regulation Of Neuron Differentiation Negative Regulation Of Smoothened Signaling Pathway Negative Regulation Of Astrocyte Differentiation Negative Regulation Of Hydrogen Peroxide-induced Cell Death
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases
GWAS		BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Estimated glomerular filtration rate ( 31015462) Hippocampal volume ( 29274321) Parkinson's disease ( 25064009 21738487) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)	Age at first sexual intercourse ( 27089180) Diverticular disease ( 30177863)
Interacting Genes		10 interacting genes: AP3S1 AP3S2 CLDN19 ERGIC3 GPR37L1 GPX8 HIBADH LAPTM4B LMNA THBS1	52 interacting genes: ADGRB3 AQP1 AQP10 ARL13B CD46 CISD2 CLDN7 CLDND2 CLEC2A CREB3L1 CYB561A3 ELOVL4 ERG28 FAM209A FFAR2 FXYD3 FXYD6-FXYD2 GPR152 GPR42 GPX8 IGFBP5 INSIG2 JAGN1 LHFPL5 PDCD1LG2 PLN PRH1 RNF122 RPRM SCARB2 SCARF1 SEC22A SERP1 SLC30A8 STOM SYNPR THAP4 THSD7B TM4SF4 TMEM147 TMEM243 TMEM248 TMEM52B TMEM54 TMEM80 TMEM86A TMEM86B TMEM97 TNFRSF10C TSPAN12 UNC93B1 UPK1B
Entrez ID		950	9283
HPRD ID		03772	13603
Ensembl ID		ENSG00000138760	ENSG00000170075
Uniprot IDs		A0A024RDG6 Q14108	O60883
PDB IDs		4F7B 4Q4B 4Q4F 4TVZ 4TW0 4TW2 5UPH 5XBM 6I2K
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?