SYTL5 and RAB27B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid)

		SYTL5	RAB27B
Description		synaptotagmin like 5	RAB27B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Exocytic Vesicle	Late Endosome Golgi Stack Plasma Membrane Apical Plasma Membrane Trans-Golgi Network Transport Vesicle Secretory Granule Platelet Dense Granule Membrane Multivesicular Body Membrane Melanosome Zymogen Granule Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane Axon Cytoplasm
	Molecular Function	Protein Binding Phospholipid Binding Small GTPase Binding Neurexin Family Protein Binding Metal Ion Binding	GTPase Activity G Protein Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	Intracellular Protein Transport Exocytosis	Melanosome Transport Positive Regulation Of Exocytosis Synaptic Vesicle Endocytosis Multivesicular Body Sorting Pathway Anterograde Axonal Protein Transport
Pathways			Platelet degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Anorexia nervosa ( 23568457) Erectile dysfunction and prostate cancer treatment ( 20932654)	Adult body size ( 32376654) Allergic disease (asthma, hay fever or eczema) ( 29083406) Body mass index ( 28892062) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143) Depression ( 29700475) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		9 interacting genes: CCDC85A CEP70 RAB27A RAB27B RAB3A RAB6A TRIM54 WAC YIF1A	19 interacting genes: CNPY2 DHPS EFHD1 GORASP2 MEX3C MLPH MYRIP NR2E1 RPH3A RPH3AL SEC11A STARD6 SYTL1 SYTL2 SYTL4 SYTL5 TUFT1 UNC13D WDR7
Entrez ID		94122	5874
HPRD ID		06736	04846
Ensembl ID		ENSG00000147041	ENSG00000041353
Uniprot IDs		Q8TDW5	O00194
PDB IDs			2F7S
Enriched GO Terms of Interacting Partners?
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