FOXP2 and GPR85

		FOXP2	GPR85
Description		forkhead box P2	G protein-coupled receptor 85
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Endoplasmic Reticulum Plasma Membrane Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding Androgen Receptor Binding	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Caudate Nucleus Development Putamen Development Cerebral Cortex Development Response To Testosterone Negative Regulation Of Transcription, DNA-templated Innate Vocalization Behavior	Signal Transduction G Protein-coupled Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Age at first birth ( 34211149 27798627) Age at first sexual intercourse ( 34211149) Attention deficit hyperactivity disorder ( 30478444) Attention deficit hyperactivity disorder or cannabis use ( 30610198) Beard thickness ( 26926045) Blood pressure (smoking interaction) ( 25189868) Body mass index ( 28892062 25673413) Brain morphology (MOSTest) ( 32665545) Cannabis use disorder ( 33096046) Childhood maltreatment ( 32066696) Chronotype ( 30696823) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Congenital heart disease (maternal effect) ( 28468790) Conotruncal heart defects (maternal effects) ( 28468790) Crohn's disease ( 22936669) Deep ovarian and/or rectovaginal disease with dense adhesions ( 28333195) Drug experimentation measurement ( 30718321) Feeling tense ( 29500382) Fish- and plant-related diet ( 32066663) Frailty index ( 34431594) Gastroesophageal reflux disease ( 31527586) General risk tolerance (MTAG) ( 30643258) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Household income (MTAG) ( 31844048) Insomnia ( 32332799) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Irritable mood ( 29500382) Major depressive disorder (MTAG) ( 33479212) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Multisite chronic pain ( 33830993 31194737) Neuroticism ( 29255261) Number of sexual partners ( 30643258) Pelvic organ prolapse (moderate/severe) ( 26545240) Schizophrenia, bipolar disorder or recurrent major depressive disorder ( 34099189) Self-reported risk-taking behaviour ( 30271922 30181555) Serum sulfate level ( 27412988) Sleep duration ( 27992416) Sleep duration (short sleep) ( 30846698) Social science traits (pleiotropy) (HIPO component 1) ( 30289880) Subcortical volume (MOSTest) ( 32665545) Urate levels in obese individuals ( 25811787) Urinary albumin-to-creatinine ratio in diabetes ( 31511532) Weight ( 28552196)	Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Triglycerides ( 25961943)
Interacting Genes		23 interacting genes: ARSB CAV1 CAV2 CCNC CDK3 CTBP1 CTBP2 FAM124A FOXP1 FOXP4 GPR85 ING3 LNX1 MAPK3 MAST3 PIAS3 PIN1 RPIA SDCBP SP4 TBR1 TLE5 TSACC	3 interacting genes: CACNB2 CXCL14 FOXP2
Entrez ID		93986	54329
HPRD ID		05611	05543
Ensembl ID		ENSG00000128573	ENSG00000164604
Uniprot IDs		B7ZLK5 O15409 Q8N6B5 Q8N6B6 X5D2H2	A4D0T8 P60893 Q8NEN2
PDB IDs		2A07 2AS5
Enriched GO Terms of Interacting Partners?
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