KIF3B and SASH1

Number of citations of the paper that reports this interaction (PubMedID 30480076)
7

Data Source:
BioGRID (two hybrid)

		KIF3B	SASH1
Description		kinesin family member 3B	SAM and SH3 domain containing 1
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GO Annotations	Cellular Component	Centrosome Cytosol Kinesin Complex Plus-end Kinesin Complex Microtubule Spindle Microtubule Cilium Microtubule Cytoskeleton Membrane Kinesin II Complex Dendrite Midbody Dendrite Cytoplasm Dendritic Spine Extracellular Exosome Ciliary Tip Axon Cytoplasm	Cytoplasm Protein-containing Complex
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity ATP Hydrolysis Activity Small GTPase Binding Intraciliary Transport Particle B Binding	G-protein Alpha-subunit Binding Protein Binding Protein C-terminus Binding Protein Kinase Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Molecular Adaptor Activity
	Biological Process	Microtubule-based Movement Mitotic Spindle Organization Mitotic Centrosome Separation Determination Of Left/right Symmetry Anterograde Axonal Transport Vesicle-mediated Transport Positive Regulation Of Cytokinesis Opsin Transport Intraciliary Transport Cilium Assembly Plus-end-directed Vesicle Transport Along Microtubule Mitotic Spindle Assembly Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex	Protein Polyubiquitination Positive Regulation Of Endothelial Cell Migration Regulation Of Epithelial Cell Migration Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of JUN Kinase Activity Positive Regulation Of Angiogenesis Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of P38MAPK Cascade Positive Regulation Of NIK/NF-kappaB Signaling Regulation Of Protein Autoubiquitination
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane MHC class II antigen presentation Intraflagellar transport COPI-dependent Golgi-to-ER retrograde traffic Kinesins Kinesins
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 27089180 34211149) Chronic obstructive pulmonary disease ( 28166215) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Granulocyte percentage of myeloid white cells ( 27863252) Inflammatory bowel disease ( 28067908) Monocyte count ( 32888494) Monocyte percentage of white cells ( 27863252)	Alzheimer's disease ( 20061627) Chronotype ( 30696823) Gait speed in old age ( 28077804) Hypothyroidism ( 27182965) Idiopathic dilated cardiomyopathy ( 29495422) Metabolite levels ( 23823483) Myocardial infarction ( 33532862) Night sleep phenotypes ( 27126917) Pneumococcal meningitis x streptococcus pneumoniae antigen allele interaction ( 31092817) Protein quantitative trait loci ( 18464913) Resting-state electroencephalogram vigilance ( 29703947) Rotator cuff tears ( 26350878) Thyroid hormone levels ( 23408906) Thyroid stimulating hormone levels ( 32769997) Type 2 diabetes nephropathy ( 21150874)
Interacting Genes		12 interacting genes: APP IFT20 KIF3A KIFAP3 LMO2 LMO4 MAP3K10 MAP3K11 NEDD4L PRC1 RAB4A SASH1	26 interacting genes: AFF1 AKAP10 ARRB1 ASCC2 C1D CCNDBP1 CNKSR1 CRK CRKL CTNNA1 EPS8L2 EXOC8 IKBKB JADE2 JADE3 KHDRBS1 KIF3B PPP4R1 RBM12B SECISBP2L SKIL SNX1 SPG7 SYNE2 TNKS2 UTRN
Entrez ID		9371	23328
HPRD ID		04781	06408
Ensembl ID		ENSG00000101350	ENSG00000111961
Uniprot IDs		O15066	O94885
PDB IDs		3B6U	2DL0 2EBP
Enriched GO Terms of Interacting Partners?
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