LHX2 and TRAPPC2L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LHX2	TRAPPC2L
Description		LIM homeobox 2	trafficking protein particle complex subunit 2L
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol TRAPP Complex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Neural Tube Closure Hair Follicle Development Regulation Of Transcription By RNA Polymerase II Axon Guidance Mesoderm Development Dorsal/ventral Pattern Formation Olfactory Bulb Development Telencephalon Regionalization Cerebral Cortex Development Neuron Differentiation Maintenance Of Epithelial Cell Apical/basal Polarity Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Axon Extension Negative Regulation Of Neurogenesis Retina Development In Camera-type Eye Positive Regulation Of Neural Precursor Cell Proliferation Negative Regulation Of Transcription Regulatory Region DNA Binding	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Pathways		Regulation of expression of SLITs and ROBOs	COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Blond vs. brown/black hair color ( 30531825) Depression ( 29700475) Hair color ( 29662168) Mercury levels ( 26025379) Post-traumatic stress disorder ( 25456346) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Waist circumference ( 23966867)	Carotid intima media thickness (mean) ( 31801372) Hair color ( 26926045)
Interacting Genes		29 interacting genes: ANKS1A ARHGAP32 BEND2 CITED2 DNMT3L ENG FLYWCH1 HOMER3 HOXC8 KHK LDB1 LGALSL LNX1 LONRF1 MORF4L1 MORN3 MSX1 OSMR PAX6 POU4F2 PPIL1 RLIM TCEANC TCP11L1 TLK1 TRAPPC2L UBTFL1 ZFP42 ZNF511	28 interacting genes: APP BLZF1 BSDC1 C11orf68 CEP57L1 GPANK1 LCN2 LHX2 LMO3 MEI4 MEOX1 MEOX2 POLR2G RABEP1 REL REPS1 SSX2 SSX2B TCF4 TRAPPC3 TRAPPC3L TRAPPC4 TRAPPC6A TRAPPC6B TRIP6 TUBB3 YPEL3 ZBTB42
Entrez ID		9355	51693
HPRD ID		04786	13711
Ensembl ID		ENSG00000106689	ENSG00000167515
Uniprot IDs		B3KNJ5 P50458	A0A0B4J294 H3BQQ8 H3BUK6 Q9UL33
PDB IDs
Enriched GO Terms of Interacting Partners?
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