SLC9A3R2 and SLC26A3

Number of citations of the paper that reports this interaction (PubMedID 12369822)
32

Data Source:
BioGRID (pull down)

		SLC9A3R2	SLC26A3
Description		SLC9A3 regulator 2	solute carrier family 26 member 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Focal Adhesion Endomembrane System Apical Plasma Membrane Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Membrane Apical Plasma Membrane Brush Border Membrane Sperm Midpiece
	Molecular Function	Signaling Receptor Binding Protein Binding Beta-catenin Binding Protein C-terminus Binding Phosphatase Binding Type 2 Metabotropic Glutamate Receptor Binding Type 3 Metabotropic Glutamate Receptor Binding Identical Protein Binding Protein-membrane Adaptor Activity Cadherin Binding	Transporter Activity Inorganic Anion Exchanger Activity Protein Binding Secondary Active Sulfate Transmembrane Transporter Activity Bicarbonate Transmembrane Transporter Activity Chloride Transmembrane Transporter Activity Sulfate Transmembrane Transporter Activity Anion:anion Antiporter Activity Oxalate Transmembrane Transporter Activity
	Biological Process	Protein-containing Complex Assembly Protein Localization To Plasma Membrane	Ion Transport Anion Transport Excretion Bicarbonate Transport Oxalate Transport Sperm Capacitation Intracellular PH Elevation Membrane Hyperpolarization Cellular Response To CAMP Sulfate Transmembrane Transport Chloride Transmembrane Transport
Pathways			Multifunctional anion exchangers Defective SLC26A3 causes congenital secretory chloride diarrhea 1 (DIAR1)
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878 30578418) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 32888494) Platelet distribution width ( 32888494) Pulse pressure ( 30578418) Red blood cell count ( 32888494) Reticulocyte count ( 32888494) Systolic blood pressure ( 27841878 30578418)	Behavioural changes in frontotemporal lobe dementia ( 29724592) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 19915573 28067908 19122664) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		43 interacting genes: ABCC4 ACE2 ACTN4 ADORA2B ADRB2 ATP2B2 CFTR DLGAP4 EZR IFT140 KCNJ1 LPAR1 LPAR2 P2RY1 PDGFRB PDPK1 PDZK1 PLCB3 PODXL PRKACA PRKCA PTEN PTH1R RDX RPS6KA1 SGK1 SGK3 SIAH1 SLC13A1 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC9A3 SLCO1A2 SLCO3A1 SRY TAFAZZIN TBC1D10A TRAF4 WWP2 WWTR1	3 interacting genes: MET SLC9A3R1 SLC9A3R2
Entrez ID		9351	1811
HPRD ID		05946	00544
Ensembl ID		ENSG00000065054	ENSG00000091138
Uniprot IDs		Q15599	P40879
PDB IDs		2D11 2HE4 2OCS 4P0C
Enriched GO Terms of Interacting Partners?
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