GTF3C4 and BRF1

Number of citations of the paper that reports this interaction (PubMedID 10523658)
38

Data Source:
HPRD (in vitro, in vivo)

		GTF3C4	BRF1
Description		general transcription factor IIIC subunit 4	BRF1 RNA polymerase III transcription initiation factor subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Transcription Factor TFIIIC Complex Nucleoplasm Mitochondrion	Transcription Factor TFIIIB Complex Nucleus Nucleoplasm Transcription Preinitiation Complex
	Molecular Function	DNA Binding Histone Acetyltransferase Activity Protein Binding Enzyme Activator Activity	RNA Polymerase III General Transcription Initiation Factor Activity RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding Protein Binding TBP-class Protein Binding Metal Ion Binding
	Biological Process	Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter Histone Acetylation 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III Regulation Of Catalytic Activity	DNA-templated Transcription, Initiation Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter RRNA Transcription TRNA Transcription Positive Regulation Of Transcription By RNA Polymerase III Transcription Preinitiation Complex Assembly
Pathways		RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS			Huntington's disease progression ( 28642124) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 22139419 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet count ( 29403010 32888494 27863252) Platelet distribution width ( 27863252) Red blood cell count ( 32888494)
Interacting Genes		14 interacting genes: AURKA BRCA1 BRF1 GTF3C1 GTF3C2 GTF3C5 GTF3C6 H3-4 H3C15 POLR3C POLR3F PRRC2B SUMO2 TBP	16 interacting genes: APP CSNK2A1 DTNBP1 GTF3C3 GTF3C4 GTF3C5 PCBD2 POLR3F RB1 RBL1 RBL2 RHOU RLIM TBP TP53 UBC
Entrez ID		9329	2972
HPRD ID		11998	05361
Ensembl ID		ENSG00000125484	ENSG00000185024
Uniprot IDs		B3KNH2 Q9UKN8	A0A024R6P8 Q92994 V9HVY2
PDB IDs
Enriched GO Terms of Interacting Partners?
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