TRIP4 and ASCC3

Number of citations of the paper that reports this interaction (PubMedID 12077347)
46

Data Source:
HPRD (in vivo, two hybrid)

		TRIP4	ASCC3
Description		thyroid hormone receptor interactor 4	activating signal cointegrator 1 complex subunit 3
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Nuclear Body Neuromuscular Junction Protein-containing Complex Activating Signal Cointegrator 1 Complex	Nucleus Nucleoplasm Cytosol Membrane Nuclear Speck Activating Signal Cointegrator 1 Complex
	Molecular Function	Protease Binding Transcription Coactivator Activity Protein Binding Zinc Ion Binding Nuclear Receptor Binding Protein Kinase Binding Estrogen Receptor Binding Histone Acetyltransferase Binding Ubiquitin-like Protein Ligase Binding	RNA Binding Protein Binding ATP Binding ATP Hydrolysis Activity 3'-5' DNA Helicase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Intracellular Estrogen Receptor Signaling Pathway Regulation Of Myoblast Differentiation Positive Regulation Of Transcription, DNA-templated Rescue Of Stalled Ribosome Toxin Transport Ribosome-associated Ubiquitin-dependent Protein Catabolic Process	DNA Dealkylation Involved In DNA Repair Cell Population Proliferation DNA Duplex Unwinding Rescue Of Stalled Ribosome Ribosome-associated Ubiquitin-dependent Protein Catabolic Process
Pathways			ALKBH3 mediated reversal of alkylation damage
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 24162737) Neuroticism ( 29255261)	Age at first sexual intercourse ( 34211149) Anxiety ( 33859377) Depression ( 33859377) Economic and political preferences (immigration/crime) ( 22566634) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Menarche (age at onset) ( 25231870) Metabolite levels ( 23823483) Multiple system atrophy (pathologically confirmed) ( 27629089) Neurociticism ( 29500382) Neuroticism ( 29255261) Number of sexual partners ( 30643258) Putamen volume ( 29147026) Smoking initiation ( 33082346) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Sub-cortical grey matter volume ( 31530798) Total cholesterol levels ( 33339817)
Interacting Genes		23 interacting genes: AR ASCC2 ASCC3 CREBBP EP300 ESR1 ESR2 GTF2A1 JUN NCOA1 NEK6 NFKB1 NR2F2 PAX9 PPARG RARA RELA RXRA SRF TBP THRB UBC XBP1	7 interacting genes: ASCC1 FAXC PTEN RPS6KA1 SKIL TRIP4 UBC
Entrez ID		9325	10973
HPRD ID		05140	09980
Ensembl ID		ENSG00000103671	ENSG00000112249
Uniprot IDs		Q15650	B4DR60 Q8N3C0
PDB IDs		2E5O	6YXQ
Enriched GO Terms of Interacting Partners?
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