TRIP12 and CARNS1

Number of citations of the paper that reports this interaction (PubMedID 12421765)
41

Data Source:
HPRD (two hybrid)

		TRIP12	CARNS1
Description		thyroid hormone receptor interactor 12	carnosine synthase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Nuclear Speck	Cellular_component Cytosol
	Molecular Function	Protein Binding Thyroid Hormone Receptor Binding Ubiquitin Protein Ligase Activity	ATP Binding Metal Ion Binding Carnosine Synthase Activity Homocarnosine Synthase Activity
	Biological Process	Protein Polyubiquitination DNA Repair Ubiquitin-dependent Protein Catabolic Process Cellular Response To DNA Damage Stimulus Regulation Of Embryonic Development Negative Regulation Of Histone H2A K63-linked Ubiquitination Regulation Of Double-strand Break Repair Negative Regulation Of Double-strand Break Repair	Histidine Catabolic Process Carnosine Biosynthetic Process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Histidine catabolism
Drugs
Diseases
GWAS		Carotid intima media thickness x smoking interaction ( 32117412) Estimated glomerular filtration rate ( 31152163 31015462) Metabolite levels ( 23823483) Systolic blood pressure ( 30224653) Weight ( 28552196)	Height ( 28552196) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494)
Interacting Genes		22 interacting genes: ATF7IP CARNS1 CDKN2A CELSR3 CLSTN1 ERG MTNR1A MTNR1B NAE1 NMI OGT PARP1 PTF1A SMAD9 SOX6 SRPK2 THRB UBC UBE2D1 UBE2D2 UBE2L3 UBE4B	2 interacting genes: PACS1 TRIP12
Entrez ID		9320	57571
HPRD ID		05144	13855
Ensembl ID		ENSG00000153827	ENSG00000172508
Uniprot IDs		A0A6Q8PGG9 A0A6Q8PHK0 Q14669	A5YM72
PDB IDs
Enriched GO Terms of Interacting Partners?
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