MS4A1 and MMD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MS4A1	MMD
Description		membrane spanning 4-domains A1	monocyte to macrophage differentiation associated
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Plasma Membrane Raft Extracellular Exosome	Lysosomal Membrane Golgi Apparatus Integral Component Of Plasma Membrane Membrane Late Endosome Membrane
	Molecular Function	Epidermal Growth Factor Receptor Binding Protein Binding Immunoglobulin Binding MHC Class II Protein Complex Binding Identical Protein Binding	Protein Kinase Activity Protein Binding Signaling Receptor Activity
	Biological Process	Store-operated Calcium Entry Humoral Immune Response Response To Bacterium B Cell Differentiation B Cell Proliferation B Cell Activation B Cell Receptor Signaling Pathway Protein Tetramerization Calcium Ion Import Into Cytosol	Protein Phosphorylation Cytolysis Regulation Of Protein Localization Positive Regulation Of Neuron Differentiation Positive Regulation Of Protein Kinase Activity
Pathways
Drugs		Rituximab Ibritumomab tiuxetan Tositumomab Ofatumumab Obinutuzumab Technetium Tc-99m nofetumomab merpentan Ocrelizumab
Diseases
GWAS		Recurrent major depressive disorder ( 29317602)	Heel bone mineral density ( 30598549) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661)
Interacting Genes		41 interacting genes: ACKR2 AQP6 CD40 CERS4 CLEC14A CREB3 CREB3L1 CSNK2A1 CSNK2A2 FAM209A FCRL3 FYN GORAB GPR42 HSD17B11 HSD17B13 IL7R KASH5 LCK LEUTX LMNA LYN MDM2 MFSD14B MMD MTIF3 REEP2 REEP4 RNF19B RNF5 SLC10A1 SLC10A6 SLC18A1 SLC35C2 THAP4 TMEM31 TMEM72 TMEM82 TMPPE TMX2 TSPO2	19 interacting genes: AGTRAP ARL13B ATP13A1 C4orf3 CYP4F2 EMC6 FAM209A GAST GPR152 GPX8 MS4A1 OCIAD1 PLEKHO1 SELENOK SFXN1 TMEM203 TMEM42 TMEM60 YIPF6
Entrez ID		931	23531
HPRD ID		00204	06835
Ensembl ID		ENSG00000156738	ENSG00000108960
Uniprot IDs		A0A024R507 P11836	A0A3B3ITQ3 Q15546
PDB IDs		1S8B 2OSL 3BKY 3PP4 6VJA 6Y90 6Y92 6Y97 6Y9A
Enriched GO Terms of Interacting Partners?
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