MRRF and WIPI2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MRRF	WIPI2
Description		mitochondrial ribosome recycling factor	WD repeat domain, phosphoinositide interacting 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Phagophore Assembly Site Nucleoplasm Autophagosome Cytosol Membrane Extrinsic Component Of Membrane Protein-containing Complex Phagophore Assembly Site Membrane
	Molecular Function	Protein Binding Ribosomal Large Subunit Binding	Protein Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Translation Ribosome Disassembly	Autophagosome Assembly Autophagy Of Mitochondrion Protein Lipidation Cellular Response To Starvation Protein Localization To Phagophore Assembly Site Autophagy Of Nucleus Protein Lipidation Involved In Autophagosome Assembly Autophagosome Maturation Xenophagy
Pathways		Mitochondrial translation termination	Macroautophagy
Drugs
Diseases
GWAS			Bone mineral density x blood lead interaction in current smokers (1df test) ( 29518117) Bone mineral density x blood lead interaction in current smokers (2df test) ( 29518117) High light scatter reticulocyte count ( 32888494) Immature fraction of reticulocytes ( 32888494 27863252) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 32888494 27863252) Red blood cell count ( 32888494)
Interacting Genes		11 interacting genes: AGTRAP APP BANP CDK5RAP2 CMTM5 FAM9B FHL3 KRT40 SYP WIPI2 ZNF408	16 interacting genes: ARL6IP1 COPS6 DDB1 DGAT2L6 FKBP7 HUWE1 MRRF MTOR OPTN POT1 RABAC1 REEP6 RPTOR STRN4 SYP TERF2IP
Entrez ID		92399	26100
HPRD ID		06856	15679
Ensembl ID		ENSG00000148187	ENSG00000157954
Uniprot IDs		Q96E11	A0A024R823 Q9Y4P8
PDB IDs		6NU2 6ZS9
Enriched GO Terms of Interacting Partners?
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