IL32 and PRTN3

Number of citations of the paper that reports this interaction (PubMedID 16488976)
41

Data Source:
HPRD (in vitro)

		IL32	PRTN3
Description		interleukin 32	proteinase 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytosol Membrane	Extracellular Region Extracellular Space Cytosol Plasma Membrane Azurophil Granule Lumen Intracellular Membrane-bounded Organelle Plasma Membrane Raft Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Cytokine Activity Protein Binding	Serine-type Endopeptidase Activity Signaling Receptor Binding Protein Binding Serine-type Peptidase Activity Enzyme Binding
	Biological Process	Defense Response Immune Response Cell Adhesion Signal Transduction	Proteolysis Membrane Protein Ectodomain Proteolysis Phagocytosis Positive Regulation Of Cell Population Proliferation Antimicrobial Humoral Response Collagen Catabolic Process Positive Regulation Of GTPase Activity Cell-cell Junction Maintenance Negative Regulation Of Phagocytosis Neutrophil Extravasation Mature Conventional Dendritic Cell Differentiation
Pathways		Other interleukin signaling RAC3 GTPase cycle	Common Pathway of Fibrin Clot Formation Other interleukin signaling Neutrophil degranulation Antimicrobial peptides
Drugs			Elafin
Diseases
GWAS		Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874) HIV-1 susceptibility ( 22174851) Liver enzyme levels (alanine transaminase) ( 33972514)	Antineutrophil cytoplasmic antibody-associated vasculitis ( 28029757) Basophil count ( 32888494) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 32888494 27863252) Blood protein levels ( 30072576 29875488) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494 27863252) White blood cell count (basophil) ( 27863252)
Interacting Genes		12 interacting genes: C1QB HSPA8 IFT140 KPNA5 NDN NQO2 PRTN3 RHBDD2 RPL4 SNRNP70 TUT1 ZFPM2	13 interacting genes: CAMP ELN F2R F2RL1 IL1B IL32 ITGB2 RELA SERPINA1 SERPINB1 SERPINB13 SMAD3 TNF
Entrez ID		9235	5657
HPRD ID		09346	01512
Ensembl ID		ENSG00000008517	ENSG00000196415
Uniprot IDs		P24001	P24158
PDB IDs			1FUJ
Enriched GO Terms of Interacting Partners?
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