DLGAP1 and MYO5A

Number of citations of the paper that reports this interaction (PubMedID 10844022)
81

Data Source:
BioGRID (pull down)

		DLGAP1	MYO5A
Description		DLG associated protein 1	myosin VA
Image
GO Annotations	Cellular Component	Cellular_component Plasma Membrane Postsynaptic Density Glutamatergic Synapse Postsynaptic Specialization	Ruffle Cytoplasm Lysosome Early Endosome Late Endosome Peroxisome Endoplasmic Reticulum Cytosol Actin Filament Actin Cytoskeleton Membrane Myosin Complex Growth Cone Vesicle Filopodium Tip Insulin-responsive Compartment Melanosome Neuron Projection Recycling Endosome Extracellular Exosome
	Molecular Function	Protein Binding Protein-containing Complex Binding Molecular Adaptor Activity	Microfilament Motor Activity RNA Binding Protein Binding Calmodulin Binding ATP Binding Small GTPase Binding Actin Filament Binding
	Biological Process	Chemical Synaptic Transmission Regulation Of Postsynaptic Neurotransmitter Receptor Activity	Post-Golgi Vesicle-mediated Transport Actin Filament Organization Protein Transport Vesicle-mediated Transport Actin Filament-based Movement Vesicle Transport Along Actin Filament Melanosome Transport Cellular Response To Insulin Stimulus Protein Localization To Plasma Membrane Regulation Of Golgi Organization
Pathways		Neurexins and neuroligins Neurexins and neuroligins	Translocation of SLC2A4 (GLUT4) to the plasma membrane Regulation of actin dynamics for phagocytic cup formation Insulin processing FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 31219225) Body fat mass ( 28552196) Cardiac Troponin-T levels ( 23247143) Eating disorders ( 22911880) Economic and political preferences (time) ( 22566634) Erythrocyte cadmium concentration in never smokers ( 27005419) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hip circumference adjusted for BMI ( 28552196) Initial alcohol sensitivity ( 30276832) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Menarche (age at onset) ( 27182965 25231870) Midgestational circulating levels of PBDEs ( 28235828) Obesity-related traits ( 23251661) Plasma free amino acid levels ( 30659259) Response to fenofibrate (total cholesterol levels) ( 27002377) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Trunk fat mass ( 28552196) Upper eyelid sagging severity ( 24869959)	Mean platelet volume ( 32888494) Metabolite levels (Pyroglutamine) ( 23934736)
Interacting Genes		24 interacting genes: APC DLG1 DLG2 DLG3 DLG4 DLGAP2 DLGAP3 DYNLL1 DYNLL2 FHL2 GRB2 GRIN2A GRIN2C ITSN1 ITSN2 KCNA4 MAGEA11 MAGI2 MYO5A SHANK1 SHANK2 SHANK3 SORBS2 TANC1	17 interacting genes: AKAP9 BMF CALM1 DLGAP1 DYNLL1 DYNLL2 KIF5B MLPH NDEL1 NEFL PRPH RAB11A RAB27A RAB3A RPH3A TRIM2 TRIM3
Entrez ID		9229	4644
HPRD ID		09260	01179
Ensembl ID		ENSG00000170579	ENSG00000197535
Uniprot IDs		A0A0A0MTP4 A8MXQ8 B7Z2J5 O14490 Q6IS01	A8CDT9 Q9UES4 Q9Y4I1
PDB IDs		5YPO	4D07 4J5L 4LLI 4LX1 4LX2 5JCY 5JCZ
Enriched GO Terms of Interacting Partners?
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