NEK9 and IFT43

		NEK9	IFT43
Description		NIMA related kinase 9	intraflagellar transport 43
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Centrosome Cytosol	Cytoplasm Cilium Microtubule Cytoskeleton Intraciliary Transport Particle A Centriolar Satellite Ciliary Tip
	Molecular Function	Protein Binding ATP Binding Protein Kinase Binding Metal Ion Binding Protein Serine Kinase Activity	Protein Binding
	Biological Process	Protein Phosphorylation Cell Cycle Cell Division	Intraciliary Retrograde Transport Cilium Assembly
Pathways		Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Pore Complex (NPC) Disassembly EML4 and NUDC in mitotic spindle formation	Intraflagellar transport
Drugs		Fostamatinib
Diseases
GWAS		Coronary artery disease ( 29212778) Feeling fed-up ( 29500382)	Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced) ( 24236485) Carpal tunnel syndrome ( 30833571) Emotional lability in attention deficit hyperactivity disorder ( 31085060)
Interacting Genes		21 interacting genes: BICD2 CSN2 GABARAP GZMB IFT43 JDP2 LIN52 MALL MAP1LC3B MBP NEK6 NEK7 NEK8 PALS1 RAN RARG RPS6KL1 SSRP1 SUPT16H TTN WDR33	3 interacting genes: LMO2 NEK9 ZMYND10
Entrez ID		91754	112752
HPRD ID		11386	14449
Ensembl ID		ENSG00000119638	ENSG00000119650
Uniprot IDs		A0A7I2V454 A0A7I2V5R1 Q6PKF2 Q8TD19	A0A024R6A9 Q96FT9
PDB IDs		3ZKE 3ZKF
Enriched GO Terms of Interacting Partners?
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