ATPAF2 and NME4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ATPAF2	NME4
Description		ATP synthase mitochondrial F1 complex assembly factor 2	NME/NM23 nucleoside diphosphate kinase 4
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Nuclear Speck	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Mitochondrial Matrix
	Molecular Function	Protein Binding	Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Metal Ion Binding Cardiolipin Binding
	Biological Process	Mitochondrial Proton-transporting ATP Synthase Complex Assembly Proton-transporting ATP Synthase Complex Assembly	Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process Lipid Transport Nucleoside Metabolic Process
Pathways			Interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Schizophrenia ( 28991256 25056061 29483656) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Body mass index ( 26426971) Red blood cell traits ( 23446634)
Interacting Genes		74 interacting genes: AKAP8L APP ATP5F1A ATP5F1B BEGAIN C11orf1 CDC14A CDK2AP1 CEP57 CFAP206 CRTC2 CTIF CYSRT1 DDIT3 DLGAP4 EBF1 EBF3 EIF4G1 EWSR1 FAM166B FCHSD2 FNTB GOLGA6L9 IKZF3 INCA1 KRT34 KRT40 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-2 KRTAP6-3 LGALS9B LNX1 LRRFIP2 LURAP1L LZTS2 MAGEA6 MEDAG MIF4GD NME4 PAK5 PKP4 POLR2J3 POLR3F POLR3H PPP1R16B PPP1R32 PRDM14 PRDM6 RAD54B RBM48 RCN1 REL RPH3AL RPIA SORBS2 SPATC1L SPG21 TCHP TERT TFIP11 TP53BP2 TRIM23 TRIM27 UBAP2 VWC2 WASHC1 ZFP90 ZNF19 ZNF23 ZNF35 ZNF426 ZNF655	40 interacting genes: ABI2 ARMC7 ATPAF2 C14orf119 C1orf109 CABP2 CABP5 CCDC102B CCDC57 CDKN2D CFAP206 CIB1 CIB3 CIDEB CLNK DTX2 HDAC7 HSF2BP LMO4 LSM8 MKRN3 MLH1 NME1 NME1-NME2 NME7 NUTF2 NXF1 POLR1C PSMB1 SOCS3 SPG21 SUV39H2 TNS4 TRAPPC2 TRAPPC2B TRIP13 TSSK3 TTC19 UBL5 ZBTB16
Entrez ID		91647	4833
HPRD ID		10599	03489
Ensembl ID		ENSG00000171953	ENSG00000103202
Uniprot IDs		Q8N5M1	A0A087WVT9 O00746
PDB IDs			1EHW
Enriched GO Terms of Interacting Partners?
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