SYNGR1 and HAS3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SYNGR1	HAS3
Description		synaptogyrin 1	hyaluronan synthase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Synaptic Vesicle Membrane Synaptic Vesicle Membrane Neuromuscular Junction Azurophil Granule Membrane Melanosome	Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Hyaluranon Cable
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Hyaluronan Synthase Activity
	Biological Process	Protein Targeting Regulated Exocytosis Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Membrane Organization Cellular Response To Leukemia Inhibitory Factor	Carbohydrate Metabolic Process Hyaluronan Biosynthetic Process Extracellular Polysaccharide Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Extracellular Matrix Assembly Positive Regulation Of Hyaluranon Cable Assembly
Pathways		Neutrophil degranulation	Hyaluronan biosynthesis and export
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Cholesteryl ester levels ( 31551469) Crohn's disease ( 28067908) Factor VIII levels ( 30586737) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG disialylation phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Inflammatory bowel disease ( 28067908) Ovarian cancer ( 30557369) Primary biliary cholangitis ( 28425483 26394269) Primary biliary cirrhosis ( 22961000) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Rheumatoid arthritis ( 32723749 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 24532676) Sleep duration (short sleep) ( 30846698) Systemic lupus erythematosus ( 33272962) Ulcerative colitis ( 28067908) vWF levels ( 30586737)	Attention deficit hyperactivity disorder ( 18821565) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure ( 30224653)
Interacting Genes		31 interacting genes: ADORA2A AQP6 CACNA1I CREB3 CREB3L1 EBP ERGIC3 FAM209A FATE1 GPR42 HAS3 LEPROT LMNA MTERF3 MYG1 NDRG4 PLEKHB2 PLIN3 PNKP RETREG3 SDCBP SLC10A6 SLC16A2 SNX1 SPG21 SPNS3 TMEM14B TMEM31 TMEM45B TMEM80 UNC93A	7 interacting genes: APOL3 C14orf180 CCR1 CMTM7 LHFPL5 PLP1 SYNGR1
Entrez ID		9145	3038
HPRD ID		06800	03889
Ensembl ID		ENSG00000100321	ENSG00000103044
Uniprot IDs		O43759	O00219 Q96RV2
PDB IDs
Enriched GO Terms of Interacting Partners?
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